Evidence map›Paper›PMID 39221408›Full record

ArticleCureus2024

Ibuprofen: The Hidden Culprit Behind Aseptic Meningitis.

Areti Kalfoutzou, Pantelis Petroulakis, Eleni Tsiouri, Theodoros Fafoutis, Adam Mylonakis, Maria Dimitrakoudi, Maria Mylonaki, Christos Piperis, Eleni Mostratou

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Areti KalfoutzouDepartment of Oncology, 251 Air Force General Hospital, Athens, GRC.
Pantelis PetroulakisSecond Department of Internal Medicine, 251 Air Force General Hospital, Athens, GRC.
Eleni TsiouriSecond Department of Internal Medicine, 251 Air Force General Hospital, Athens, GRC.
Theodoros FafoutisSecond Department of Internal Medicine, 251 Air Force General Hospital, Athens, GRC.
Adam MylonakisFirst Department of Surgery, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Maria DimitrakoudiDepartment of Hematology, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Maria MylonakiDepartment of Radiology, Papanikolaou General Hospital, Thessaloniki, GRC.
Christos PiperisDepartment of Cardiology, Gennimatas General Hospital, Athens, GRC.
Eleni MostratouSecond Department of Internal Medicine, 251 Air Force General Hospital, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced aseptic meningitis represents a significant clinical entity characterized by an inflammatory response of the meninges triggered by specific pharmacological agents. This condition predominantly manifests as a delayed hypersensitivity reaction to a variety of drugs, most notably non-steroidal anti-inflammatory drugs, antibiotics, immune checkpoint inhibitors, and monoclonal antibodies. We report a case of aseptic meningitis in a 54-year-old male presenting with nausea and blurred vision two hours after taking ibuprofen. This case aims to highlight one underrecognized adverse event associated with one of the most commonly used over-the-counter medications worldwide.

Indexed as

aseptic meningitisdelayed hypersensitivitydrugsibuprofennsaids

Identifiers

PMID39221408
PMCPMC11365196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.