Evidence map›Paper›PMID 39221247›Full record

ArticleFrontiers in immunology2024

E-cigarette exposure disrupts antitumor immunity and promotes metastasis.

Marcel Arias-Badia, Chien-Chun Steven Pai, PeiXi Chen, Anthony Chang, Yee May Lwin, Aahir Srinath, Jeffrey E Gotts, Stanton A Glantz, Lawrence Fong

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Biomarkers of Exposure to Tobacco-Related Toxicants and Oxidative Stress Among Cancer Survivors.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  3. Review
  4. Review
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcel Arias-BadiaDivision of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Chien-Chun Steven PaiDivision of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
PeiXi ChenDivision of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Anthony ChangDivision of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Yee May LwinDivision of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Aahir SrinathDivision of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Jeffrey E GottsKaiser Permanente San Francisco Medical Center, San Francisco, CA, United States.
Stanton A Glantz *Center for Tobacco Control Research and Education, University of California, San Francisco, San Francisco, CA, United States.
Lawrence Fong *Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electronic cigarettes (e-cigarettes) are thought to pose low risk of cancer because the components of e-cigarette liquid are not carcinogens. We analyzed the effects of the two major components, PG/VG and nicotine, on tumor development in preclinical models. We found that PG/VG promoted tumor cell migration in migration assays and contributed to more aggressive, metastatic, and immunosuppressive tumors

Indexed as

Electronic Nicotine Delivery SystemsNicotineAnimalsCell Line, TumorCell MovementCTLA-4 AntigenFemaleMiceMice, Inbred C57BLNeoplasm MetastasisProgrammed Cell Death 1 ReceptorCTLA-4 AntigenCtla4 protein, mouseNicotineProgrammed Cell Death 1 Receptorelectronic cigarettesimmune checkpoint blockadeimmunosuppressionmetastasiswhole body exposure

Identifiers

PMID39221247
PMCPMC11365074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.