Evidence map›Paper›PMID 39221210›Full record

ReviewMaterials today. Bio2024

Lateral flow assays: Progress and evolution of recent trends in point-of-care applications.

Saloni Kakkar, Payal Gupta, Shiv Pratap Singh Yadav, Divakar Raj, Garima Singh, Sakshi Chauhan, Manoj Kumar Mishra, Elena Martín-Ortega, Stefano Chiussi, Krishna Kant

Abstract readReview
In one paragraph

Review in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  11. Rapid serological detection of smoothFrontiers in cellular and infection microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saloni KakkarCouncil of Scientific and Industrial Research (CSIR)- Centre for Cellular & Molecular Biology (CCMB), Hyderabad, 500007, India.
Payal GuptaDepartment of Biotechnology, Graphic Era (Deemed to be University), Dehradun, 248002, India.
Shiv Pratap Singh YadavCouncil of Scientific and Industrial Research (CSIR)- Centre for Cellular & Molecular Biology (CCMB), Hyderabad, 500007, India.
Divakar RajDepartment of Allied Sciences, School of Health Sciences and Technology, UPES, Dehradun, 248007, India.
Garima SinghDepartment of Allied Sciences, School of Health Sciences and Technology, UPES, Dehradun, 248007, India.
Sakshi ChauhanDept. of Cardiothoracic and Vascular Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Manoj Kumar MishraDepartment of Biotechnology, Rama University, Kanpur, 209217, India.
Elena Martín-OrtegaIFCAE, Research Institute of Physics and Aerospace Science, Universidade de Vigo, Ourense, 32004, Spain.
Stefano ChiussiCINTECX, Universidade de Vigo, New Materials Group, Vigo, 36310, Spain.
Krishna KantCINBIO, Universidade de Vigo, Campus Universitario As Lagoas Marcosende, Vigo, 36310, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paper based point-of-care (PoC) detection platforms applying lateral flow assays (LFAs) have gained paramount approval in the diagnostic domain as well as in environmental applications owing to their ease of utility, low cost, and rapid signal readout. It has centralized the aspect of self-evaluation exhibiting promising potential in the last global pandemic era of Covid-19 implementing rapid management of public health in remote areas. In this perspective, the present review is focused towards landscaping the current framework of LFAs along with integration of components and characteristics for improving the assay by pushing the detection limits. The review highlights the synergistic aspects of assay designing, sample enrichment strategies, novel nanomaterials-based signal transducers, and high-end analytical techniques that contribute significantly towards sensitivity and specificity enhancement. Various recent studies are discussed supporting the innovations in LFA systems that focus upon the accuracy and reliability of rapid PoC testing. The review also provides a comprehensive overview of all the possible difficulties in commercialization of LFAs subjecting its applicability to pathogen surveillance, water and food testing, disease diagnostics, as well as to agriculture and environmental issues.

Indexed as

Analytical techniquesLateral-flow assaysNanomaterialsPoint-of-care detectionSample enrichmentSignal amplification

Identifiers

PMID39221210
PMCPMC11364909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.