Evidence map›Paper›PMID 39221200›Full record

ArticleMaterials today. Bio2024

Novel multidomain peptide self-assembly biomaterials based on bola structure and terminal anchoring: Nanotechnology meets antimicrobial therapy.

Weikang Yu, Xu Guo, Xuefeng Li, Yingxin Wei, Yinfeng Lyu, Licong Zhang, Jiajun Wang, Anshan Shan

Abstract read
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Weikang YuCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.
Xu GuoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.
Xuefeng LiCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.
Yingxin WeiCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.
Yinfeng LyuCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.
Licong ZhangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.
Jiajun WangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.
Anshan ShanCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To ameliorate the diminished antimicrobial efficiency and physiological stability associated with monomeric antimicrobial peptides (AMPs) molecules, future research will focus on the artificial design of self-assembling peptides to replace monomeric entities, aiming to combat the antibiotic resistance crisis caused by microbial infections. In this study, the "bola" structure was used as the foundational architecture driving molecular self-assembly, with hydrophobic amino acids at the termini to anchor and finely adjust the sequence, thereby organizing a range of novel multidomain peptides (MDPs) templates into an ABA block motif. The results indicate that FW2 (GM

Indexed as

Antibacterial mechanismsAntimicrobial peptideBola structureSelf-assemblyTerminal anchoring

Identifiers

PMID39221200
PMCPMC11363844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.