Evidence map›Paper›PMID 39220718›Full record

ArticleAmerican heart journal plus : cardiology research and practice2024

Protocol-driven approach to guideline-directed medical therapy optimization for heart failure: A real-world application to recovery.

Crystal Lihong Yan, David Snipelisky, Mauricio Velez, David Baran, Jerry D Estep, E Joseph Bauerlein, Nina Thakkar Rivera

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American heart journal plus : cardiology research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Crystal Lihong YanDivison of Internal Medicine, University of Miami Health System, Miami, FL, USA.
David SnipeliskyHeart, Vascular & Thoracic Institute, Cleveland Clinic Florida, Weston, FL, USA.
Mauricio VelezHeart, Vascular & Thoracic Institute, Cleveland Clinic Florida, Weston, FL, USA.
David BaranHeart, Vascular & Thoracic Institute, Cleveland Clinic Florida, Weston, FL, USA.
Jerry D EstepHeart, Vascular & Thoracic Institute, Cleveland Clinic Florida, Weston, FL, USA.
E Joseph BauerleinMiami Transplant Institute, Jackson Health System, Miami, FL, USA.
Nina Thakkar RiveraHeart, Vascular & Thoracic Institute, Cleveland Clinic Florida, Weston, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of our study was to evaluate the real-world effects of an aggressive, personalized protocol for guideline-directed medical therapy (GDMT) titration in patients with heart failure (HF) with reduced ejection fraction (HFrEF). We conducted a two-center retrospective cohort study. Patients with HFrEF who presented to a HF clinic from January 2020 to December 2022 were placed on a GDMT protocol. 180 patients were included in the study. Mean GDMT score significantly increased from 4.7 to 5.9 (

Indexed as

Guideline-directed medical therapyHeart failureProtocolReduced ejection fractionTitration

Identifiers

PMID39220718
PMCPMC11362780

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.