Evidence map›Paper›PMID 39220574›Full record

ArticleAsia Pacific allergy2024

Successful desensitization to atezolizumab-induced near-fatal anaphylaxis in patients with hepatocellular carcinoma: A case report and literature review.

Ji Hyun Oh, Kwang Il Seo, Hee-Kyoo Kim, Gil-Soon Choi

Abstract readCase Reports
In one paragraph

Article in Asia Pacific allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ji Hyun OhDepartment of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.ORCID https://orcid.org/0000-0002-9491-0405
Kwang Il SeoDepartment of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.ORCID https://orcid.org/0000-0001-8854-5205
Hee-Kyoo KimDepartment of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.ORCID https://orcid.org/0000-0003-0692-1639
Gil-Soon ChoiDepartment of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.ORCID https://orcid.org/0000-0003-3466-3294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atezolizumab, a humanized antiprogrammed death ligand 1 monoclonal immunoglobulin G1 antibody, is a targeted therapeutic drug known as an immune checkpoint inhibitor. It is currently used to treat various types of cancer, including unresectable hepatocellular carcinoma (HCC), nonsmall cell lung cancer, urothelial cancer, and breast cancer, and is becoming a therapeutic option in the forefront of oncology treatment. However, it may sometimes lead to undesirable adverse reactions owing to the activation of immune responses in various organs. Cutaneous adverse reactions to atezolizumab are well known; however, cases of anaphylaxis are very rare. In this report, we present the first case of HCC who experienced near-fatal anaphylaxis to atezolizumab in South Korea.

Indexed as

Anaphylaxisatezolizumabdesensitizationhypersensitivity

Identifiers

PMID39220574
PMCPMC11365681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.