ReviewIntractable & rare diseases research2024
Spontaneous pneumomediastinum: A comprehensive review of diagnosis and management.
Review in Intractable & rare diseases research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Article
- Optimising Autologous Breast Reconstruction: Pneumothorax and Pneumomediastinum-A Literature Review and First Reported Case of Pneumomediastinum Following Bilateral DIEP Flap Reconstruction.Journal of personalized medicine · 2026Review
- Probable pregabalin and amantadine-containing cold medication intoxication in an adolescent with rhabdomyolysis: Case report.Journal of Taibah University Medical Sciences · 2026Article
- Secondary Pneumomediastinum Following Bronchoscopic Interventions in Patients With Prolonged Tracheostomy Intubation: A Case Series.The American journal of case reports · 2026Article
- Article
- Spontaneous Pneumomediastinum Following Severe Vomiting in a Previously Healthy Young Adult.Cureus · 2026Article
- Article
- Article
- Article
- Case Report: Spontaneous Pneumomediastinum and Pneumothorax Complicating Severe Ketoacidosis-An Unexpected Presentation.Reports (MDPI) · 2025Article
- Article
- Spontaneous Pneumomediastinum: A Narrative Review Offering a New Perspective on Its Definition and Classification.Cureus · 2025Review
- Severe chest and back pain due to extra-pulmonary emphysema above 5,000 m: a series of case reports.Frontiers in medicine · 2025Article
- Streptococcus salivarius pneumonia-associated pneumomediastinum: a case report and literature review.BMC infectious diseases · 2024Review
- Pneumomediastinum due to excessive cheering during a football match.Turkish journal of emergency medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pneumomediastinum is a rare condition defined by the presence of air in the mediastinum. In the absence of traumatic injury, iatrogenic injury, or clear etiology, it is called spontaneous pneumomediastinum (SPM). Spontaneous pneumomediastinum most commonly occurs in younger individuals and has a self-limiting course with a good outcome. The purpose of the present manuscript is to systematically review the existing literature on SPM evaluation and management for updated clinical understanding of this condition. A literature search was conducted of publications about SPM on MEDLINE/PubMed and Google Scholar by identifying all the articles with key search terms "pneumomediastinum" and "spontaneous pneumomediastinum". Inclusion criteria were case series published in English between 1980 and 2023. In total, 24 case series were selected and reviewed to determine presenting symptoms, clinical signs and predisposing factors associated with spontaneous pneumomediastinum. Most patients were male; the average age at diagnosis was 26.3 years. The most common presenting symptoms were chest pain and dyspnea. The most common exam finding was subcutaneous emphysema, in 35.4% of patients. Only 5.9% had the classic Hamman's sign. Risk factors include history of asthma, history of smoking, and recent physical activity. This manuscript presents an extensive review of relevant literature highlighting the diagnosis and essential management of spontaneous pneumomediastinum.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.