High drug-pathogen mismatch in the management of invasive carbapenem-resistant

Olukemi Adekanmbi, Oluwafemi Popoola, Adeola Fowotade, Olusola Idowu, Babatunde Ogunbosi, Sulaiman Lakoh, Ini Adebiyi

Abstract read

In one paragraph

Article in IJID regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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2 · The registry

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Olukemi AdekanmbiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Oluwafemi PopoolaDepartment of Community Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Adeola FowotadeDepartment of Medical Microbiology and Parasitology, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Olusola IdowuDepartment of Anaesthesia, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Babatunde OgunbosiDepartment of Paediatrics, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Sulaiman LakohDepartment of Medicine, College of Medicine and Allied Sciences, University of Sierra Leone, Freetown, Sierra Leone.

Ini AdebiyiDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to provide lacking data on antibiotics and treatment strategies used in the management of carbapenem-resistant Methods: A cross-sectional study was carried out at the University College Hospital in Ibadan. CRE isolated from routine culture of specimens from hospitalized patients from December 2021 to September 2022 was identified. Treatment information and other data were collected from the patients' medical records. Results: The hospital laboratory isolated CRE from 55 patients during the study period and 27 (49.1%) of them had data available for the study. The most frequently isolated CRE was Conclusions: Despite culture data, we found a high prevalence of drug-pathogen mismatch in CRE treatment, including new or persistent use of antibiotics, to which resistance was documented. Antimicrobial stewardship efforts need to be strengthened to specifically address CRE treatment and effective antibiotics need to be made accessible.

Indexed as

Antimicrobial resistanceAntimicrobial stewardshipBacteriaCarbapenem-resistant EnterobacteriaceaeInfection prevention and control

Identifiers

PMID39220204

DOI10.1016/j.ijregi.2024.100407

PMCPMC11363559

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