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ArticleIJID regions2024

A new case of Echovirus 11 neonatal fulminant hepatitis involving male twins in a Northern Italy Tertiary University Hospital: Insight on a possible immunological clue.

Federica Novazzi, Antonio Piralla, Simona Perniciaro, Angelo Paolo Genoni, Francesca Drago Ferrante, Federica Giardina, Guglielmo Ferrari, Laura Pellegrinelli, Nicola Clementi, Elena Pariani and 4 more

Abstract readCase Reports
In one paragraph

Article in IJID regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Federica NovazziUniversity of Insubria, Department of Medicine and Technological Innovation Varese, Varese, Italy.
Antonio PirallaFondazione IRCCS Policlinico San Matteo, Microbiology and Virology Department, Pavia, Italy.
Simona PerniciaroOspedale Filippo del Ponte Ostetricia e Ginecologia, Neonatology and NICU, Del Ponte Hospital, Varese, Italy.
Angelo Paolo GenoniUniversity of Insubria, Department of Medicine and Technological Innovation Varese, Varese, Italy.
Francesca Drago FerranteASST Sette Laghi, Laboratory of Medical Microbiology and Virology, Varese, Italy.
Federica GiardinaUniversity of Pavia, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences Pavia, Pavia, Italy.
Guglielmo FerrariFondazione IRCCS Policlinico San Matteo, Microbiology and Virology Department, Pavia, Italy.
Laura PellegrinelliUniversity of Milan, Department of Biomedical Sciences for Health Milano, Milano, Italy.
Nicola ClementiIRCCS San Raffaele Hospital, Milan, Italy, Department of Biomedical Sciences for Health, Milano, Italy.
Elena ParianiUniversity of Milan, Department of Biomedical Sciences for Health Milano, Milano, Italy.
Ivan ZanoniHarvard University, Boston Children's Hospital Cambridge, Cambridge, USA.
Fausto BaldantiFondazione IRCCS Policlinico San Matteo, Microbiology and Virology Department, Pavia, Italy.
Massimo AgostiUniversity of Insubria, Department of Medicine and Surgery, Varese, Italy.
Nicasio ManciniUniversity of Insubria, Department of Medicine and Technological Innovation Varese, Varese, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Center for Disease Prevention and Control has reported 19 cases of severe echovirus 11 infections in neonates since 2022, nine of which were fatal. We report a new fatal neonatal case that occurred in a male twin for which we evaluated the respiratory and intestinal mucosal innate immune response.

Indexed as

Echovirus 11EnterovirusHepatitisMucosal immunityNeonatal infection

Identifiers

PMID39220203
PMCPMC11363566

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.