Evidence map›Paper›PMID 39220150›Full record

ArticleJournal of analytical atomic spectrometry2024

Improvement in the sensitivity of LA-ICP-MS bioimaging by addition of nitrogen to the argon carrier gas.

Monique G Mello, Thomas E Lockwood, Jonathan Wanagat, Mika T Westerhausen, David P Bishop

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of analytical atomic spectrometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monique G MelloHyphenated Mass Spectrometry Laboratory, Faculty of Science, University of Technology Sydney, P.O. Box 123, Broadway, NSW 2007, Australia.
Thomas E LockwoodHyphenated Mass Spectrometry Laboratory, Faculty of Science, University of Technology Sydney, P.O. Box 123, Broadway, NSW 2007, Australia.
Jonathan WanagatDivision of Geriatrics, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Mika T WesterhausenHyphenated Mass Spectrometry Laboratory, Faculty of Science, University of Technology Sydney, P.O. Box 123, Broadway, NSW 2007, Australia.
David P BishopHyphenated Mass Spectrometry Laboratory, Faculty of Science, University of Technology Sydney, P.O. Box 123, Broadway, NSW 2007, Australia.

Funding

Mitochondrial DNA Deletion Mutation Frequency as a Metric of Biologic AgeR01AG069924 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jonathan Wanagat · 2022 to 2026
$2.1M
Mitochondrial biogenesis, genetics and cell loss in mammalian agingR01AG055518 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AIKEN, JUDD M., HERBST, ALLEN · 2017 to 2022
$2.0M
Mitochondrial biogenesis, genetics and cell loss in mammalian agingK02AG059847 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WANAGAT, JONATHAN · 2018 to 2022
$801k
NIA NIH HHS K02 AG059847NIA NIH HHS R01 AG055518NIA NIH HHS R01 AG069924
6 · The paper itself

Abstract

Elemental bioimaging of low abundant elements via laser ablation-inductively coupled plasma mass spectrometry (LA-ICP-MS) is hampered by a lack of sensitivity. Novel solutions for specific applications have been developed, however there is a need for more universal approaches. Here we investigated the addition of N

Indexed as

Gas additionLA-ICP-MSMixed carrier gasSignal enhancement

Identifiers

PMID39220150
PMCPMC11361726

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.