ArticleWorld journal of gastrointestinal surgery2024
Systemic immune-inflammation index combined with pediatric appendicitis score in assessing the severity and prognosis for paediatric appendicitis.
Article in World journal of gastrointestinal surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A Prospective Model for Detecting Missed Appendicitis in Low-Risk Pediatric Patients.Indian journal of pediatrics · 2026Article
- Routine Biomarkers in Paediatric Appendicitis Stratification: Which Add Diagnostic Value? A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Systemic immune inflammatory index (SII) as a predictive marker for the failure of air enema treatment in children with Ileocolic intussusception: a case-control study.BMC pediatrics · 2025Article
- The Role of Emerging Immune-Inflammatory Indexes in the Preoperative Differentiation of Complicated and Uncomplicated Acute Appendicitis: A Single-Center Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Clinical significance of the systemic immune-inflammation index in relation to pathology, treatment and outcomes in acute appendicitis: a retrospective study.Annals of medicine · 2025Article
- The Role of Systemic Immune-Inflammation Index (SII) in Diagnosing Pediatric Acute Appendicitis.Diagnostics (Basel, Switzerland) · 2025Article
- Evaluation of Systemic Inflammation in Children with Untreated Dental Caries.Oral health & preventive dentistry · 2025Article
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3 authors.
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Abstract
backgroundPediatric appendicitis is a common cause of abdominal pain in children and is recognized as a significant surgical emergency. A prompt and accurate diagnosis is essential to prevent complications such as perforation and peritonitis.
aimTo investigate the predictive value of the systemic immune-inflammation index (SII) combined with the pediatric appendicitis score (PAS) for the assessment of disease severity and surgical outcomes in children aged 5 years and older with appendicitis.
methodsClinical data of 104 children diagnosed with acute appendicitis were analyzed. The participants were categorized into the acute appendicitis group and chronic appendicitis group based on disease presentation and further stratified into the good prognosis group and poor prognosis group based on prognosis. The SII and PAS were measured, and a joint model using the combined SII and PAS was constructed to predict disease severity and surgical outcomes.
resultsSignificant differences were observed in the SII and PAS parameters between the acute appendicitis group and chronic appendicitis group. Correlation analysis showed associations among the SII, PAS, and disease severity, with the combined SII and PAS model demonstrating significant predictive value for assessing disease severity [aera under the curve (AUC) = 0.914] and predicting surgical outcomes (AUC = 0.857) in children aged 5 years and older with appendicitis.
conclusionThe study findings support the potential of integrating the SII with the PAS for assessing disease severity and predicting surgical outcomes in pediatric appendicitis, indicating the clinical utility of the combined SII and PAS model in guiding clinical decision-making and optimizing surgical management strategies for pediatric patients with appendicitis.
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