Evidence map›Paper›PMID 39219968›Full record

ReviewCureus2024

Pathophysiology and Evolving Treatment Options of Septic Arthritis: A Narrative Review.

Alan D Kaye, Driskell Greene, Alana V Alvarez-Amado, Horace L Townsend, Michael Forte, Megan Vasterling, Jon D Hirsch, Jeffrey Howard, Shahab Ahmadzadeh, Olga Willett and 3 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. [Management of emergencies in rheumatology].Zeitschrift fur Rheumatologie · 2026
    Review
  2. Septic knee: multimodality approach.Skeletal radiology · 2026
    Review
  3. Article
  4. Article
  5. [Management of emergencies in rheumatology].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026
    Review
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Driskell GreeneDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Alana V Alvarez-AmadoSchool of Medicine, American University of the Caribbean, Cupecoy, SXM.
Horace L TownsendSchool of Medicine, American University of the Caribbean, Cupecoy, SXM.
Michael ForteSchool of Medicine, Louisiana State University Health Sciences Center New Orleans, New Orleans, USA.
Megan VasterlingSchool of Medicine, Louisiana State University Health Sciences Center New Orleans, New Orleans, USA.
Jon D HirschDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Jeffrey HowardDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Shahab AhmadzadehDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Olga WillettDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Adam M KayeDepartment of Pharmacy Practice, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Giustino VarrassiDepartment of Pain Medicine, Paolo Procacci Foundation, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyogenic (septic) arthritis is a severe joint infection characterized by the invasion of microorganisms into the synovium, causing inflammation and joint destruction. This review article provides a comprehensive overview of pyogenic arthritis, focusing on etiology, pathogenesis, clinical manifestations, diagnosis, and management strategies. This review explores routes of microbial entry into joints, emphasizing the importance of prompt identification and treatment to prevent irreversible joint damage. Clinical manifestations, such as joint pain, swelling, and limited range of motion, are discussed, along with the challenges in differentiating pyogenic arthritis from other joint disorders. Diagnostic approaches, including joint aspiration and imaging modalities, are critically examined for accuracy in confirming diagnosis. This review also addresses the significance of early intervention through antimicrobial therapy and joint drainage, highlighting the role of multidisciplinary collaboration in optimizing patient outcomes. In summary, the present investigation underscores the complexities of pyogenic arthritis and the need for a comprehensive understanding of pathophysiology for timely and effective management to improve patient prognosis and quality of life.

Indexed as

antibioticarticular involvementpyogenic arthritisseptic arthritisstaphylococcusstreptococcus

Identifiers

PMID39219968
PMCPMC11364462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.