Evidence map›Paper›PMID 39219944›Full record

ArticleCureus2024

Comparative Evaluation of Colistin-Susceptibility Testing in Carbapenem-Resistant Klebsiella pneumoniae Using VITEK, Colistin Broth Disc Elution, and Colistin Broth Microdilution.

Tessa Antony, Yugadharshini Senthilnathan, Rukmani Madhavakumar, Premika Amudhan, Shruthi Venkataraman, Sanjana Rally, Ravi S Pitani, Ilakkiya Arumugam

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tessa AntonyMicrobiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Yugadharshini SenthilnathanMicrobiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Rukmani MadhavakumarMicrobiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Premika AmudhanMicrobiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Shruthi VenkataramanMicrobiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Sanjana RallyMicrobiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Ravi S PitaniCommunity Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Ilakkiya ArumugamMicrobiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study aimed to compare the results of colistin-susceptibility testing performed using the automated VITEK system, colistin broth microdilution (BMD), and colistin broth disk elution (CBDE) methods. MATERIALS AND

methodsThis exploratory study was conducted in a tertiary care center in South India. Carbapenem-resistant

resultsAmong the 49 carbapenem-resistant

conclusionCBDE is a reliable and cost-effective method that can be adopted in the routine microbiology laboratory for colistin-susceptibility testing, as it does not require any specialized equipment or techniques and is 100% consistent with the gold standard BMD method. Although the automated VITEK system is used in most routine microbiological laboratories for antibiotic-susceptibility testing, it cannot be reliably used for colistin-susceptibility testing due to its high error rates (very major error rate of 28.5%; major error rate of 2.4%).

Indexed as

broth microdilutioncarbapenem resistancecolistin broth disk elutioncolistin resistanceklebsiella pneumoniae (kp)

Identifiers

PMID39219944
PMCPMC11362344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.