Evidence map›Paper›PMID 39219844›Full record

ArticleRSC advances2024

Inhalable drug-loaded silk fibroin carriers for pulmonary drug delivery.

Ilenia D'Onofrio, Giuseppe De Giorgio, Roman Sajapin, Davide Vurro, Aris Liboà, Elena Dembech, Giovanna Trevisi, Maddalena Botti, Vardan Galstyan, Giuseppe Tarabella and 1 more

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Aerosol Jet Printing in Biotechnologies.Bioengineering (Basel, Switzerland) · 2026
    Review
  2. Recycled Sericin Biopolymer in Biotechnology and Bioelectronics.Bioengineering (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ilenia D'OnofrioInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.ORCID https://orcid.org/0009-0008-6154-0461
Giuseppe De GiorgioInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.ORCID https://orcid.org/0000-0001-7368-2629
Roman SajapinInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.
Davide VurroInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.
Aris LiboàInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.
Elena DembechInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.
Giovanna TrevisiInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.
Maddalena BottiInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.
Vardan GalstyanInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.ORCID https://orcid.org/0000-0002-0615-3097
Giuseppe TarabellaInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.ORCID https://orcid.org/0000-0002-8898-714X
Pasquale D'AngeloInstitute of Materials for Electronics and Magnetism, IMEM-CNR P.co Area delle Scienze 37/A 43124 Parma Italy giuseppedegiorgio@cnr.it giuseppe.tarabella@cnr.it.ORCID https://orcid.org/0000-0002-4500-4457

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The design and development of engineered micro and nano-carriers offering superior therapeutic performance compared to traditional delivery forms, are crucial in pharmaceutical research. Aerosolization and inhalation of carriers with improved solubility/stability of insoluble drugs, has huge potential for targeted drug delivery (DD) in various pulmonary diseases. Indeed, dedicated carriers must meet specific dimensional rules for proper lung delivery. Particles between 2-10 μm in size are normally deposited in the tracheobronchial region, while particles of 0.5-2 μm may be properly deposited in the alveoli. In this work, we report the development of inhalable nanostructured carries made of a 'green' bio-inspired polymer from aqueous solutions,

Identifiers

PMID39219844
PMCPMC11362913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.