Evidence map›Paper›PMID 39219779›Full record

ArticleClinical case reports2024

Psychedelic-assisted therapy for palliative care within a home treatment setting: A case report.

Seragnoli Federico, Martignoni Geo, Martignoni Entela, Silke Bachmann, Rabitti Elisa, Cavuto Silvio, Dubus Zoë, Penzenstadler Louise, Thorens Gabriel, Billieux Joël and 1 more

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Seragnoli FedericoPsychiatry Department Geneva University Hospitals Geneva Switzerland.ORCID https://orcid.org/0000-0001-9261-770X
Martignoni GeoPrivate practice Gordola, Ticino Switzerland.
Martignoni EntelaPrivate practice Gordola, Ticino Switzerland.
Silke BachmannPsychiatry Department Geneva University Hospitals Geneva Switzerland.ORCID https://orcid.org/0000-0001-6436-6376
Rabitti ElisaPsycho-Oncology Unit Azienda USL-IRCCS di Reggio Emilia Reggio Emilia Italy.ORCID https://orcid.org/0000-0002-0246-2327
Cavuto SilvioClinical Trial Center-Statistics Unit, SOC Infrastructure, Research and Statistics Azienda USL-IRCCS di Reggio Emilia Reggio Emilia Italy.ORCID https://orcid.org/0000-0002-2845-9310
Dubus ZoëDepartment of History, College of Arts and Science USASK Saskatoon Saskatchewan Canada.
Penzenstadler LouisePsychiatry Department Geneva University Hospitals Geneva Switzerland.
Thorens GabrielPsychiatry Department Geneva University Hospitals Geneva Switzerland.
Billieux JoëlInstitute of Psychology University of Lausanne Lausanne Switzerland.ORCID https://orcid.org/0000-0002-7388-6194
Zullino DanielePsychiatry Department Geneva University Hospitals Geneva Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key Clinical Message: This case study describes the feasibility and safety of psychedelic-assisted therapy (PAT) as a home-based intervention for a patient with throat cancer experiencing significant existential distress. The patient tolerated the intervention well. This case supports the feasibility and safety of PAT for patients with life-threatening conditions in a home setting. Abstract: Psychedelic-assisted therapy (PAT), as it is practiced today, merges traditional psychotherapeutic techniques with the use of psychedelics such as LSD, psilocybin, or MDMA with the aim of unlocking deeper insights in patients and treating mental conditions that are resistant to other forms of therapy. The present case study describes the safety of PAT as a home-based intervention for a patient with throat cancer experiencing significant existential distress. The patient tolerated the intervention well and was asked to report on measures of anxiety, depression, and distress related to his somatic condition. The observations provided by this clinical case report align with previous findings, suggesting that PAT can be safely applied to potentially provide relief from existential distress in patients with life-threatening conditions. As this is a single-case study, generalizations should be made cautiously. Moreover, placebo effects, expectancy effects, and the natural course of the disease may influence outcomes. Future research should consider controlled trials to ascertain the efficacy and safety of such interventions in diverse settings.

Indexed as

home treatmentpalliative carepsychedelicpsychedelic‐assisted therapythroat cancer

Identifiers

PMID39219779
PMCPMC11364487

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.