Evidence map›Paper›PMID 39219718›Full record

ArticleFrontiers in toxicology2024

Effect of altered production and storage of dopamine on development and behavior in

Irene Lee, Ava C Knickerbocker, Charlotte R Depew, Elizabeth L Martin, Jocelyn Dicent, Gary W Miller, Meghan L Bucher

Abstract read
In one paragraph

Article in Frontiers in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. The dopaminergic system ofRoyal Society open science · 2025
    Review
  4. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Irene Lee *Department of Environmental Health Sciences, Mailman School of Public Health at Columbia University, New York, NY, United States.
Ava C Knickerbocker *Department of Environmental Health Sciences, Mailman School of Public Health at Columbia University, New York, NY, United States.
Charlotte R DepewDepartment of Environmental Health Sciences, Mailman School of Public Health at Columbia University, New York, NY, United States.
Elizabeth L MartinDepartment of Environmental Health Sciences, Mailman School of Public Health at Columbia University, New York, NY, United States.
Jocelyn DicentDepartment of Environmental Health Sciences, Mailman School of Public Health at Columbia University, New York, NY, United States.
Gary W MillerDepartment of Environmental Health Sciences, Mailman School of Public Health at Columbia University, New York, NY, United States.
Meghan L BucherDepartment of Environmental Health Sciences, Mailman School of Public Health at Columbia University, New York, NY, United States.

Funding

Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
Genetic Epidemiology and Multi-Omics Analyses in Familial and Sporadic Alzheimer's Disease Among Secular Caribbean Hispanics and Religious OrderR01AG067501 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P, MILLER, GARY W · 2020 to 2024
$11.7M
Epidemiological Integration of Genetic Variants and Metabolomics Profiles in Washington Heights Columbia Aging ProjectRF1AG066107 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P, MILLER, GARY W · 2020 to 2022
$11.4M
Vesicular Modulation of Dopamine Neuron ToxicityR01ES023839 · NIEHS · EMORY UNIVERSITY · PI MILLER, GARY W · 2015 to 2025
$5.0M
U2C Experimental CoreU2CES030163 · NIEHS · EMORY UNIVERSITY · PI JONES, DEAN PAUL, LI, SHUZHAO · 2018 to 2021
$3.6M
A Practical Tool for Managing the Complexity of Biologics Process ManufacturingR44TR000187 · NCATS · ADVANCED PROCESS COMBINATORICS, INC. · PI PEKNY, JOSEPH F · 2014 to 2015
$1.2M
A Practical Tool for Managing the Complexity of Biologics Process ManufacturingR43TR000187 · NCATS · ADVANCED PROCESS COMBINATORICS, INC. · PI PEKNY, JOSEPH F · 2012 to 2012
$150k
NCATS NIH HHS R43 TR000187NCATS NIH HHS R44 TR000187NIA NIH HHS R01 AG067501NIA NIH HHS RF1 AG066107NIEHS NIH HHS R01 ES023839NIEHS NIH HHS T32 ES007322NIEHS NIH HHS U2C ES030163
6 · The paper itself

Abstract

Introduction: The nematode, Methods: We studied Results: Our results further implicate proper dopamine synthesis and sequestration in the regulation of Discussion: Our results provide additional evidence that the dopamine system impacts the development, growth, and reproduction in

Indexed as

Caenorhabditis elegansdopamineneurodevelopmentneuroscienceneurotoxicity

Identifiers

PMID39219718
PMCPMC11363549

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.