Evidence map›Paper›PMID 39219619›Full record

ArticleFrontiers in bioengineering and biotechnology2024

The effects of antimicrobial peptides buCaTHL4B and Im-4 on infectious root canal biofilms.

Ziqiu Hu, Haixia Ren, Yifan Min, Yixin Li, Yuyuan Zhang, Min Mao, Weidong Leng, Lingyun Xia

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziqiu Hu *Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Haixia Ren *Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Yifan Min *Department of Stomatology, Zhushan County People's Hospital, Shiyan, China.
Yixin LiDepartment of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Yuyuan ZhangDepartment of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Min MaoDepartment of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Weidong LengDepartment of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Lingyun XiaDepartment of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The primary cause of pulp and periapical diseases is the invasion of bacteria into the root canal, which results from the continuous destruction of dental hard tissues. Effective management of infections during root canal therapy necessitates effectively irrigation. This study aims to investigate the effects of two antimicrobial peptides (AMPs), buCaTHL4B and Im-4, on root canal biofilms Methods: Two-species biofilms ( Results: Compared to 1% NaOCl, 10 μg/mL buCaTHL4B or Im-4 exhibited significantly greater bactericidal effects on the two-species biofilms ( Conclusion: buCaTHL4B and Im-4 exhibited remarkable antibacterial and anti-biofilm capabilities against pathogenic root canal biofilms

Indexed as

antimicrobial peptideapical periodontitisbuCaTHL4BEnterococcus faecalisFusobacterium nucleatumIm-4

Identifiers

PMID39219619
PMCPMC11361941

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.