Evidence map›Paper›PMID 39219456›Full record

ArticleHaematologica2025

Hodgkin/Reed-Sternberg cells induce GPNMB expression and release from macrophages to suppress T-cell responses to the Epstein-Barr virus-encoded LMP2A protein.

Navta Masand, Tracey A Perry, Matthew Pugh, Eanna Fennell, Aoife Hennessy, Wenbin Wei, Katerina Bouchalova, David Burns, Pamela Kearns, Graham Taylor and 2 more

Abstract read
In one paragraph

Article in Haematologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Navta MasandInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham.
Tracey A PerryInstitute of Cancer and Genomic Sciences, University of Birmingham.
Matthew PughInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham.
Eanna FennellLimerick Digital Cancer Research Centre, Bernal Institute and Health Research Institute and School of Medicine, University of Limerick, Limerick.
Aoife HennessyLimerick Digital Cancer Research Centre, Bernal Institute and Health Research Institute and School of Medicine, University of Limerick, Limerick.
Wenbin WeiInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; The Palatine Centre, Durham University, Durham.
Katerina BouchalovaDepartment of Pediatrics, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc, Czech Republic.
David BurnsUniversity Hospitals Plymouth NHS Trust, Plymouth.
Pamela KearnsInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre University of Birmingham, Birmingham.
Graham TaylorInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham.
Katerina VrzalikovaInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom; Royal College of Surgeons in Ireland Medical University of Bahrain, Manama, PO Box 15503, Bahrain. k.vrzalikova@bham.ac.uk.
Paul G MurrayLimerick Digital Cancer Research Centre, Bernal Institute and Health Research Institute and School of Medicine, University of Limerick, Limerick, Ireland; Royal College of Surgeons in Ireland Medical University of Bahrain, Manama, Bahrain; Department of Clinical and Molecular Pathology, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc. paul.murray@ul.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39219456
PMCPMC11694118

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.