Evidence map›Paper›PMID 39219432›Full record

ReviewCurrent medicinal chemistry2025

Epitranscriptome: A Novel Regulatory Layer during Atherosclerosis Progression.

Concetta Schiano, Ugo Trama, Enrico Coscioni, Teresa Infante, Annapaola Coppola, Filomena de Nigris, Claudio Napoli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Concetta SchianoDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania Luigi Vanvitelli, Naples, 80138, Italy.ORCID 0000-0002-2570-6910
Ugo TramaGeneral Direction for Health Protection, Coordination of the Campania Regional Health System, Naples, 80132, Italy.ORCID 0000-0001-9473-8943
Enrico CoscioniDivision of Cardiac Surgery, AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, 84131, Italy.ORCID 0000-0002-4373-3760
Teresa InfanteDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania Luigi Vanvitelli, Naples, 80138, Italy.ORCID 0000-0002-1764-9610
Annapaola CoppolaDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania Luigi Vanvitelli, Naples, 80138, Italy.ORCID 0000-0002-5788-5722
Filomena de NigrisDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, 80138, Italy.ORCID 0000-0002-2322-1557
Claudio NapoliDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania Luigi Vanvitelli, Naples, 80138, Italy.ORCID 0000-0002-5455-555X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA modifications have recently gained great attention due to their extensive regulatory effects in a wide range of cellular networks and signaling pathways. In cardiovascular diseases (CVDs), several RNA changes, called "epitranscriptome" alterations, are found in all RNA molecules (tRNA, rRNA, mRNA, and ncRNAs). Unlike the epigenetic process, which influences the progression of atherosclerosis (AS), its transcriptional and post-transcriptional regulatory mechanisms are still unknown. Here, we described the main epitranscriptome signs to provide new insights into AS, including m

Indexed as

AtherosclerosisEpigenesis, GeneticTranscriptomeAnimalsDisease ProgressionHumansatherosclerosiscardiovascular diseaseEpitranscriptomeprecision medicineRNAsignaling pathways.

Identifiers

PMID39219432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.