Evidence map›Paper›PMID 39219426›Full record

ReviewPharmaceutical nanotechnology2025

Liquid Crystalline Lipid Nanoparticles: Emerging Trends and Applications in Skin Cancer.

Kamya Varshney, Rupa Mazumder, Anjna Rani, Pratibha Pandey, Malakapogu Ravindra Babu

Abstract readReview
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In one paragraph

Review in Pharmaceutical nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Circular RNAs modulate cancer drug resistance: advances and challenges.Cancer drug resistance (Alhambra, Calif.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kamya VarshneyNoida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, Uttar Pradesh-201306, India.
Rupa MazumderNoida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, Uttar Pradesh-201306, India.ORCID 0000-0002-1888-548X
Anjna RaniNoida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, Uttar Pradesh-201306, India.
Pratibha PandeyNoida Institute of Engineering and Technology, Greater Noida, Uttar Pradesh-201306, India.
Malakapogu Ravindra BabuLovely Professional University, Phagwara, Panjab, India.ORCID 0000-0002-4672-1650

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid crystalline lipid nanoparticles (LCNPs) represent a type of membrane-based nano-carriers formed through the self-assembly of lyotropic lipids. These lipids, such as unsaturated monoglycerides, phospholipids, and co-lipids, create liquid crystals or vesicles with an aqueous core enclosed by a natural or synthetic phospholipid bilayer upon exposure to an aqueous medium. Liquid crystalline lipid nanoparticles (LCNPs), akin to liposomes, have garnered significant attention as nanocarriers suitable for a diverse range of hydrophobic and hydrophilic molecules. Their notable structural advantage lies in a mono-channel network organization and the presence of multiple compartments, resulting in heightened encapsulation efficiency for various substances. Cubosomes, spongosomes, hexosomes, and multicompartment nanoparticles are examples of lipid nanocarriers with interior liquid crystalline structures that have recently gained a lot of interest as effective drug delivery systems. Additionally, LCNPs facilitate the sustained release of encapsulated compounds, including therapeutic macromolecules. This review delves into the structure of liquid crystalline lipid nanoparticles, explores preparation techniques, and outlines their applications in the context of skin cancer.

Indexed as

Antineoplastic AgentsLipidsLiquid CrystalsNanoparticlesSkin NeoplasmsAnimalsDrug CarriersDrug Delivery SystemsHumansAntineoplastic AgentsDrug CarriersLipidscharacterizationcubosomeshexosomesLiquid crystalline lipid nanoparticlesnanoparticlesphospholipidspreparation.Skin cancerspongosomes

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.