Evidence map›Paper›PMID 39219265›Full record

ArticleMolecular medicine reports2024

Indole‑3‑propionic acid alleviates intestinal epithelial cell injury via regulation of the TLR4/NF‑κB pathway to improve intestinal barrier function.

Ying Chen, Yu Li, Xiaojuan Li, Qingqing Fang, Feng Li, Shiyao Chen, Weichang Chen

Abstract read
In one paragraph

Article in Molecular medicine reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. International journal of molecular sciences · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying Chen *Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, P.R. China.
Yu Li *Department of Gastroenterology and Hepatology, Minhang Hospital, Fudan University, Shanghai 201100, P.R. China.
Xiaojuan LiDepartment of Gastroenterology and Hepatology, Minhang Hospital, Fudan University, Shanghai 201100, P.R. China.
Qingqing FangDepartment of Gastroenterology and Hepatology, Minhang Hospital, Fudan University, Shanghai 201100, P.R. China.
Feng LiDepartment of Gastroenterology and Hepatology, Minhang Hospital, Fudan University, Shanghai 201100, P.R. China.
Shiyao ChenDepartment of Gastroenterology and Hepatology, Minhang Hospital, Fudan University, Shanghai 201100, P.R. China.
Weichang ChenDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indole‑3‑propionic acid (IPA), a product of

Indexed as

ApoptosisEpithelial CellsIndolesIntestinal MucosaLipopolysaccharidesNF-kappa BSignal TransductionToll-Like Receptor 4Cell LineCell SurvivalHumansIntestinal Barrier Functionindolepropionic acidIndolesLipopolysaccharidesNF-kappa BTLR4 protein, humanToll-Like Receptor 4intestinal epithelial barrierIPALPSpro‑inflammatory cytokineTJ proteins

Identifiers

PMID39219265
PMCPMC11350629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.