Evidence map›Paper›PMID 39219179›Full record

ArticleMagnetic resonance in medicine2025

T1 and T2 measurements across multiple 0.55T MRI systems using open-source vendor-neutral sequences.

Kathryn E Keenan, Bilal Tasdelen, Ahsan Javed, Rajiv Ramasawmy, Rudy Rizzo, Michele N Martin, Karl F Stupic, Nicole Seiberlich, Adrienne E Campbell-Washburn, Krishna S Nayak

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Feasibility of tagged MRI at 0.55 T.Magnetic resonance in medicine · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Repeatability and reproducibility of rapid TImaging neuroscience (Cambridge, Mass.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kathryn E KeenanNational Institute of Standards and Technology, Boulder, Colorado, USA.ORCID 0000-0001-9070-5255
Bilal TasdelenMing Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-6462-3651
Ahsan JavedCardiovascular Branch, Division of Intramural Research, National Heart, Lung, Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0003-1311-1247
Rajiv RamasawmyCardiovascular Branch, Division of Intramural Research, National Heart, Lung, Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Rudy RizzoDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Michele N MartinNational Institute of Standards and Technology, Boulder, Colorado, USA.
Karl F StupicNational Institute of Standards and Technology, Boulder, Colorado, USA.
Nicole SeiberlichDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Adrienne E Campbell-WashburnCardiovascular Branch, Division of Intramural Research, National Heart, Lung, Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-7169-5693
Krishna S NayakMing Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-5735-3550

Funding

Development of high-performance low field MRI technology ZIAHL006257 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CAMPBELL-WASHBURN, ADRIENNE · 2021 to 2025
$8.1M
Intramural NIH HHS ZIA HL006257National Institutes of Health, Intramural Research Program, National Heart Lung and Blood Institute Z01-HL006257National Science Foundation 1828736
6 · The paper itself

Abstract

purposeTo compare T1 and T2 measurements across commercial and prototype 0.55T MRI systems in both phantom and healthy participants using the same vendor-neutral pulse sequences, reconstruction, and analysis methods.

methodsStandard spin echo measurements and abbreviated protocol measurements of T1, B1, and T2 were made on two prototype 0.55 T systems and two commercial 0.55T systems using an ISMRM/NIST system phantom. Additionally, five healthy participants were imaged at each system using the abbreviated protocol for T1, B1, and T2 measurement. The phantom measurements were compared to NMR-based reference measurements to determine accuracy, and both phantom and in vivo measurements were compared to assess reproducibility and differences between the prototype and commercial systems.

resultsVendor-neutral sequences were implemented across all four systems, and the code for pulse sequences and reconstruction is freely available. For participants, there was no difference in the mean T1 and T2 relaxation times between the prototype and commercial systems. In the phantom, there were no significant differences between the prototype and commercial systems for T1 and T2 measurements using the abbreviated protocol.

conclusionQuantitative T1 and T2 measurements at 0.55T in phantom and healthy participants are not statistically different across the prototype and commercial systems.

Indexed as

Magnetic Resonance ImagingPhantoms, ImagingAdultAlgorithmsEquipment DesignFemaleHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMaleReproducibility of ResultsSensitivity and Specificity0.55Tmulti‐site repeatabilityT1T2

Identifiers

PMID39219179
PMCPMC11518643

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.