ArticleAnnals of intensive care2024
Surgical site infection in severe trauma patients in intensive care: epidemiology and risk factors.
Article in Annals of intensive care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of risk prediction models for surgical site infection after abdominal surgery in adults.Frontiers in public health · 2026Pooled it
- Open Fractures in Polytrauma and Non-Polytrauma Patients: Outcomes and Predictive Factors in a Level III Trauma Center.Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca · 2026Article
- Surgical site infection incidence and surgical antibiotic prophylaxis in the ICU patient: a multicenter observational study.Journal of intensive care · 2026Article
- A pilot study on microbial dynamics in drainage fluid during trauma recovery.Annals of surgical treatment and research · 2026Article
- Staged management of severe polytrauma with pericardial and diaphragmatic rupture and open pelvic ring injury: a case report with literature review.International journal of surgery case reports · 2026Article
- Surgical site infection after femoral fracture surgery: 5-year trends in mechanisms of injury, pathogens, and antimicrobial resistance.Journal of orthopaedic surgery and research · 2026Article
- Risk Factors and Clinical Outcomes of Deep Surgical Site Infections in Trauma Patients: A National Database Analysis.Healthcare (Basel, Switzerland) · 2025Article
- Surgical site infections: a comprehensive review.Journal of trauma and injury · 2025Article
- Predictive model of surgical infection to enhance patient safety: A retrospective cohort study.Revista da Escola de Enfermagem da U S P · 2025Article
- Comment to: Clinical outcomes of triclosan-coated barbed suture in open hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
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15 authors.
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Abstract
backgroundSevere trauma is the leading cause of disability and mortality in the patients under 35 years of age. Surgical site infections (SSI) represent a significant complication in this patient population. However, they are often inadequately investigated, potentially impacting the quality of patient outcomes. The aim of this study was to investigate the epidemiology of SSI and risk factors in severe trauma patients.
methodsWe conducted a multicenter retrospective cohort study screening the severe trauma patients (STP) admitted to two intensive care units of an academic institution in Marseille between years2018 and 2019. Those who underwent orthopedic or spinal surgery within 5 days after admission were included and classified into two groups according to the occurrence of SSI (defined by the Centers for Disease Control (CDC) international diagnostic criteria) or not. Our secondary goal was to evaluate STP survival at 48 months, risk factors for SSI and microbiological features of SSI.
resultsForty-seven (23%) out of 207 STP developed an SSI. Mortality at 48-months did not differ between SSI and non-SSI patients (12.7% vs. 10.0%; p = 0.59). The fractures of 22 (47%) severe trauma patients with SSI were classified as Cauchoix 3 grade and 18 (38%) SSI were associated with the need for external fixators. Thirty (64%) severe trauma patients with SSI had polymicrobial infection, including 34 (72%) due to Gram-positive cocci. Empirical antibiotic therapy was effective in 31 (66%) cases. Multivariate analysis revealed that risk factors such as low hemoglobin, arterial oxygenation levels, hyperlactatemia, high serum creatinine and glycemia, and Cauchoix 3 grade on the day of surgery were associated with SSI in severe trauma patients. The generated predictive model showed a good prognosis performance with an AUC of 0.80 [0.73-0.88] and a high NPV of 95.9 [88.6-98.5] %.
conclusionsOur study found a high rate of SSI in severe trauma patients, although SSI was not associated with 48-month mortality. Several modifiable risk factors for SSI may be effectively managed through enhanced perioperative monitoring and the implementation of a patient blood management strategy.
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