Evidence map›Paper›PMID 39218965›Full record

Observational studyScientific reports2024

Association of office blood pressure with ischemic and bleeding events in patients undergoing percutaneous coronary intervention.

Byung Sik Kim, Jeong-Hun Shin, Woohyeun Kim, Hyungdon Kook, Yonggu Lee, Jin-Kyu Park, Jinho Shin, Young-Hyo Lim

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05935397 (HanYang University Medical Center), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05935397 unknown statusnot on this map

HanYang University Medical Center (HYUMC) PCI Registry

Typeobservational_patient_registrySponsorHanyang University Seoul HospitalRan2012 to 2025Enrolled5,000ConditionsCoronary Artery Stenosis, Coronary Artery Disease, Blood PressureArmspercutaneous coronary intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Byung Sik Kim *Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Guri Hospital, Guri, Republic of Korea.
Jeong-Hun Shin *Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Guri Hospital, Guri, Republic of Korea.
Woohyeun KimDivision of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Seoul Hospital, 222 Wangsimni-ro, Sungdong-gu, Seoul, 04763, Republic of Korea.
Hyungdon KookDivision of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Seoul Hospital, 222 Wangsimni-ro, Sungdong-gu, Seoul, 04763, Republic of Korea.
Yonggu LeeDivision of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Guri Hospital, Guri, Republic of Korea.
Jin-Kyu ParkDivision of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Seoul Hospital, 222 Wangsimni-ro, Sungdong-gu, Seoul, 04763, Republic of Korea.
Jinho ShinDivision of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Seoul Hospital, 222 Wangsimni-ro, Sungdong-gu, Seoul, 04763, Republic of Korea.
Young-Hyo LimDivision of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Seoul Hospital, 222 Wangsimni-ro, Sungdong-gu, Seoul, 04763, Republic of Korea. mdoim@hanyang.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimal blood pressure (BP) for patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) remains unclear. This study aims to identify the optimal BP by investigating the association between average office BP and future clinical events in patients undergoing PCI. Consecutive patients undergoing PCI from 2012 to 2016 were included. They were divided into five groups according to the average follow-up BP after discharge. The co-primary outcomes were net adverse clinical events (NACE) and major adverse cardiac and cerebrovascular events (MACCE) up to 5 years. NACE was defined as a composite of MACCE (all-cause death, non-fatal myocardial infarction (MI), non-fatal stroke, or any revascularization) or major bleeding. A total of 2845 patients were included, and among them, 787 (27.7%) experienced the NACE during the follow-up period. Patients in the highest SBP group (adjusted hazard ratio [HR] 1.495, confidence interval [CI] 1.189-1.880) and lowest SBP group (adjusted HR 1.625, CI 1.214-2.176) had a significantly higher risk of 5-year NACE. Similar associations were observed between SBP and the risk of MACCE, and similar results based on DBP categories were also observed. There was a J-curve relationship between SBP and DBP with respect to 5-year NACE and MACCE. The nadir point of risk for NACE and MACCE was found at 121.4/74.8 and 120.4/73.7 mmHg. In patients underwent PCI, there is a significant correlation between office BP level and clinical events, indicates the importance of efforts for optimal BP control to reduce ischemic and bleeding events.Trial registration: HanYang University Medical Center (HYUMC) Registry, NCT05935397.

Indexed as

Blood PressureCoronary Artery DiseaseHemorrhagePercutaneous Coronary InterventionAgedAged, 80 and overFemaleHumansMaleMiddle AgedMyocardial InfarctionRisk FactorsBlood pressureCoronary artery diseaseHypertensionPercutaneous coronary intervention

Identifiers

PMID39218965
PMCPMC11366747

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.