Evidence map›Paper›PMID 39218881›Full record

ArticleBMC public health2024

Longitudinal relationship between pre-exposure prophylaxis motivation and change in adherence among men who have sex with men in Western China.

Bing Lin, Jiaxiu Liu, Haiying Pan, Wei He, Hong Zhang, Xiaoni Zhong

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Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bing LinSchool of Public Health, Chongqing Medical University, Yuzhong District, No.1 Medical College Road, Chongqing, 400016, China.
Jiaxiu LiuSchool of Medical Informatics, Chongqing Medical University, Chongqing, China.
Haiying PanSchool of Public Health, Chongqing Medical University, Yuzhong District, No.1 Medical College Road, Chongqing, 400016, China.
Wei HeSchool of Public Health, Chongqing Medical University, Yuzhong District, No.1 Medical College Road, Chongqing, 400016, China.
Hong ZhangSchool of Public Health, Chongqing Medical University, Yuzhong District, No.1 Medical College Road, Chongqing, 400016, China.
Xiaoni ZhongSchool of Public Health, Chongqing Medical University, Yuzhong District, No.1 Medical College Road, Chongqing, 400016, China. zhongxiaoni@cqmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe efficacy of pre-exposure prophylaxis (PrEP) is highly dependent on adherence, and adherence behavior is influenced by motivation. The aim of this study was to explore the longitudinal relationship between PrEP motivation and change in adherence among men who have sex with men (MSM) in Western China.

methodsFrom November 2019 to June 2021, we conducted a PrEP prospective cohort study. Motivation to take medicine was measured by the PrEP Motivation Scale at baseline, and was grouped into different levels of latent categories by Latent Profile Analysis (LPA). A multinomial logistic regression model was used to explore the longitudinal relationship between change in adherence (improvement, decline, no change) and different levels of PrEP motivation.

resultsMSM were divided into two categories of PrEP motivation, a "high motivation group" (n = 506, 69.89%) and a "low motivation group" (n = 218, 30.11%). High PrEP motivation had no significant effect on the change in short-term adherence, however, it contributed to the improvement in long-term adherence [odds ratio (OR) = 3.028 (1.100-8.332), p = 0.031]. The predictive power of the adherence model was significantly enhanced with the addition of the PrEP motivation factor.

conclusionsThere was a positive correlation between high PrEP motivation at baseline and an improvement in long-term adherence. Surveillance and intervention of PrEP motivation in MSM can increase their adherence, and then promote PrEP efficacy.

Indexed as

Drug MonitoringHIV InfectionsHomosexuality, MaleMedication AdherenceMotivationPre-Exposure ProphylaxisAdultChinaHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesYoung AdultAdherenceCohort studyLatent profile analysisMen who have sex with menMotivationPre-exposure prophylaxis

Identifiers

PMID39218881
PMCPMC11367776

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.