Evidence map›Paper›PMID 39218826›Full record

ArticleEJNMMI reports2024

3D dynamic diuretic renal scintigraphy using a hybrid whole body CZT SPECT/CT camera protocol in the evaluation of acute ureteric obstruction caused by ureteric stone.

Miguel Ochoa-Figueroa, Klara Borbely, Diana Hasselqvist, Fredrik Askling, Tobias Lööw, Firas Aljabery, Veronica Sanchez-Rodriguez

Abstract read
In one paragraph

Article in EJNMMI reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miguel Ochoa-FigueroaDepartment of Clinical Physiology in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping University, 581 85, Linköping, Sweden. miguel.ochoa.figueroa@regionostergotland.se.ORCID http://orcid.org/0000-0001-9444-8225
Klara BorbelyDepartment of Radiology in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Diana HasselqvistEmergency Department in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Fredrik AsklingDepartment of Clinical Physiology in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping University, 581 85, Linköping, Sweden.
Tobias LööwDepartment of Clinical Physiology in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping University, 581 85, Linköping, Sweden.
Firas AljaberyDivision of Urology, Department of Clinical and Experimental Medicine, Linköping University Hospital, Linköping, Sweden.
Veronica Sanchez-RodriguezDepartment of Clinical Physiology in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping University, 581 85, Linköping, Sweden.

Funding

Forsknings- och stipendieförvaltningen i Östergötland RÖ-930637
6 · The paper itself

Abstract

purposeTo investigate the performance of dynamic 3D diuretic renal scintigraphy using a hybrid whole body CZT SPECT/CT for the evaluation of acute ureteric obstruction in patients with urinary stone disease.

methods20 patients who presented to the Emergency Department with acute renal colic due to urinary stone disease confirmed by means of CT were prospectively included. Three observers evaluated and graded hydronephrosis, hydroureter, perirenal stranding, and thickening of the renal fascia from the CT as well as the renal scintigraphy curves from the dynamic SPECT study. The normalized residual activity from dynamic SPECT was analysed at 16 min in all patients and at 20 min in suspected obstruction.

resultsRenal scintigraphy curves showed a sensitivity of 100%, specificity of 93%, PPV 83% and a NPV 100% for obstruction, while normalized residual activity showed a sensitivity of 100%, specificity of 73%, PPV 56% and a NPV 100%. All patients presented at least 2 secondary signs of obstruction on the CT, showing a PPV of only 25% for obstruction.

conclusionDynamic 3D diuretic renal scintigraphy CZT SPECT/CT provides valuable functional and anatomical information from one single examination. The combination of pathological renogram curves and high normalized residual activity values provide the most valuable imaging information to determine the presence of acute ureteric obstruction. The secondary signs of obstruction observed on CT are not specific and should not be used to confirm or discard obstruction in patients with urinary stone disease.

trial registrationISRCTN15338358. Registration date 03/01/2024. Retrospectively registered. https://www.isrctn.com/ISRCTN15338358?q=miguel%20ochoa%20figueroa&filters=&sort=&offset=1&totalResults=2&page=1&pageSize=10.

Indexed as

Cadmium-zinc-tellurideCTSPECTStoneUreteral obstruction

Identifiers

PMID39218826
PMCPMC11366731

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.