Evidence map›Paper›PMID 39218605›Full record

ArticleSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2024

[Study on direct ventricular assist loading mode based on a finite element method].

Chen Li, Xianjie Jiang, Sheng Zhang, Tianbo Wang, Xiaohan Liu, Yue Zhang, Gang Huang, Xiaogang Zhang, Junbo Xu, Zhongmin Jin

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Chen LiSchool of Mechanical Engineering, Southwest Jiaotong University, Chengdu 610031, P. R. China.
Xianjie JiangSchool of Mechanical Engineering, Southwest Jiaotong University, Chengdu 610031, P. R. China.
Sheng ZhangSchool of Mechanical Engineering, Southwest Jiaotong University, Chengdu 610031, P. R. China.
Tianbo WangThe third people's hospital of Chengdu (Affiliated hospital of Southwest Jiaotong University), Chengdu 610031, P. R. China.
Xiaohan LiuThe third people's hospital of Chengdu (Affiliated hospital of Southwest Jiaotong University), Chengdu 610031, P. R. China.
Yue ZhangThe third people's hospital of Chengdu (Affiliated hospital of Southwest Jiaotong University), Chengdu 610031, P. R. China.
Gang HuangThe third people's hospital of Chengdu (Affiliated hospital of Southwest Jiaotong University), Chengdu 610031, P. R. China.
Xiaogang ZhangSchool of Mechanical Engineering, Southwest Jiaotong University, Chengdu 610031, P. R. China.
Junbo XuThe third people's hospital of Chengdu (Affiliated hospital of Southwest Jiaotong University), Chengdu 610031, P. R. China.
Zhongmin JinSchool of Mechanical Engineering, Southwest Jiaotong University, Chengdu 610031, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the biomechanical effects of direct ventricular assistance and explore the optimal loading mode, this study established a left ventricular model of heart failure patients based on the finite element method. It proposed a loading mode that maintains peak pressure compression, and compared it with the traditional sinusoidal loading mode from both hemodynamic and biomechanical perspectives. The results showed that both modes significantly improved hemodynamic parameters, with ejection fraction increased from a baseline of 29.33% to 37.32% and 37.77%, respectively, while peak pressure, stroke volume, and stroke work parameters also increased. Additionally, both modes showed improvements in stress concentration and excessive fiber strain. Moreover, considering the phase error of the assist device's working cycle, the proposed assist mode in this study was less affected. Therefore, this research may provide theoretical support for the design and optimization of direct ventricular assist devices.

Indexed as

Finite Element AnalysisHeart-Assist DevicesHeart FailureBiomechanical PhenomenaHeart VentriclesHemodynamicsHumansModels, CardiovascularStress, MechanicalStroke VolumeEpicardial assistanceFinite elementHeart failureHemodynamics

Identifiers

PMID39218605
PMCPMC11366469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.