Evidence map›Paper›PMID 39218457›Full record

ArticleSaudi medical journal2024

Is postoperative adjuvant radiotherapy necessary for patients with esophageal cancer after neoadjuvant chemoradiotherapy? An analysis based on the SEER database.

Qiuying An, Yuhao Su, Yajing Wang, Chanjun Zhen, Wenwen Bai, Liyuan Fu, Yibing Liu, Ping Zhang, Zhiguo Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qiuying AnFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Yuhao SuFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Yajing WangFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Chanjun ZhenFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Wenwen BaiFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Liyuan FuFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Yibing LiuFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Ping ZhangFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.
Zhiguo ZhouFrom the Department of Radiation Oncology (An, Su, Wang, Zhen, Bai, Fu, Zhang, Zhou) and from the Department of Medical Oncology (Liu), The Fourth Hospital of Hebei Medical University, Hebei Province, China.ORCID https://orcid.org/0000-0002-5373-8098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the outcomes of adjuvant radiotherapy in patients with esophageal cancer (EC) who underwent esophagectomy following neoadjuvant chemoradiotherapy (NCRT).

methodsThe data of EC patients who received adjuvant therapy after NCRT between 2004 to 2019 was retrieved from the SEER database. The patients were split into the adjuvant radiotherapy with or without chemotherapy (RT±CT) and the adjuvant chemotherapy (CT) groups. The process of propensity score matching (PSM) was employed.

resultsFollowing PSM, 157 patients in total were recruited in each treatment group. There were no significant variations in either overall survival (OS) or cancer-specific survival (CSS) between the RT±CT and CT groups (median OS: 28 months versus. 51 months,

conclusionRadiotherapy-based adjuvant therapy does not significantly improve the prognosis of EC patients after NCRT, although it may provide a survival benefit for patients with cT3-4 tumors in N-stage downstaging.

Indexed as

Esophageal NeoplasmsEsophagectomyNeoadjuvant TherapySEER ProgramAgedChemoradiotherapy, AdjuvantChemotherapy, AdjuvantFemaleHumansMaleMiddle AgedNeoplasm StagingPropensity ScoreRadiotherapy, AdjuvantSurvival Rateadjuvant therapyesophageal canceresophagectomyneoadjuvant chemoradiotherapySEER

Identifiers

PMID39218457
PMCPMC11376696

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.