Evidence map›Paper›PMID 39217276›Full record

ArticleDiscover nano2024

Biogenically synthesized green silver nanoparticles exhibit antimalarial activity.

Savitri Tiwari, Reetesh Kumar, Sonia Devi, Prakriti Sharma, Neil Roy Chaudhary, Sushmita Negi, Nikunj Tandel, Srujan Marepally, Sylviane Pied, Rajeev K Tyagi

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Savitri Tiwari *School of Biological and Life Sciences, Galgotias University, Gautam Buddha Nagar, Greater Noida, 201310, India.
Reetesh Kumar *Faculty of Agricultural Sciences, Institute of Applied Sciences and Humanities, GLA University, Mathura, 281406, India.
Sonia Devi *Biomedical Parasitology and Translational-Immunology Lab, Division of Cell Biology and Immunology, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh, 160036, India.
Prakriti SharmaBiomedical Parasitology and Translational-Immunology Lab, Division of Cell Biology and Immunology, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh, 160036, India.
Neil Roy ChaudharyBiomedical Parasitology and Translational-Immunology Lab, Division of Cell Biology and Immunology, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh, 160036, India.
Sushmita NegiBiomedical Parasitology and Translational-Immunology Lab, Division of Cell Biology and Immunology, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh, 160036, India.
Nikunj TandelInstitute of Science, Nirma University, Ahmedabad, Gujarat, India.
Srujan MarepallyCentre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu, 632002, India.
Sylviane PiedCNRS UMR 9017-INSERM U1019, Center for Infection and Immunity of Lille-9 CIIL, Institut Pasteur de Lille, University of Lille, 59019, Lille, France.
Rajeev K TyagiBiomedical Parasitology and Translational-Immunology Lab, Division of Cell Biology and Immunology, CSIR-Institute of Microbial Technology (IMTECH), Sec-39A, Chandigarh, 160036, India. rajeevtyagi@imtech.res.in.

Funding

Department of Biotechnology, Ministry of Science and Technology, India BT/RLF/Re-entry/27/2018Indian Council of Medical Research 35/1/2020-Nano/BMS
6 · The paper itself

Abstract

The suboptimal efficacies of existing anti-malarial drugs attributed to the emergence of drug resistance dampen the clinical outcomes. Hence, there is a need for developing novel drug and drug targets. Recently silver nanoparticles (AgNPs) constructed with the leaf extracts of Euphorbia cotinifolia were shown to possess antimalarial activity. Therefore, the synthesized AgNPs from Euphorbia cotinifolia (EcAgNPs) were tested for their parasite clearance activity. We determined the antimalarial activity in the asexual blood stage infection of 3D7 (laboratory strain) P. falciparum. EcAgNPs demonstrated the significant inhibition of parasite growth (EC

Indexed as

ApoptosisCell deathDrug resistanceEuphorbia cotinifoliaNanoparticlePlasmodium falciparumReactive oxygen species (ROS) production

Identifiers

PMID39217276
PMCPMC11365884

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.