ArticleScientific reports2024
Altered muscle synergy structure in patients with poststroke stiff knee gait.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Relationship between lower limb muscle coordination and knee flexion angle during the swing phase of gait in post-stroke individuals.Journal of neuroengineering and rehabilitation · 2026Article
- Effects of Robot-Assisted Gait Training on Stage-Based Lower Limb Motor Recovery and Muscle Tone in Subacute Stroke: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Reproducible candidate kinematic-electromyographic waveform markers of post-stroke gait from public multimodal waveform exports.Frontiers in medical technology · 2026Article
- Development and preliminary validation of a multimodal instrument for spasticity quantification using a composite index: A pilot study.PloS one · 2026Article
- Neuromechanical Predictors of Clinical Scores of Balance and Functional Mobility in Chronic Stroke Survivors - A Machine Learning Approach.medRxiv : the preprint server for health sciences · 2025Article
- Mechanisms of Post-stroke Stiff-Knee Gait: A Narrative Review.American journal of physical medicine & rehabilitation · 2025Review
- Deficit in intersegmental torques drives post-stroke stiff-knee gait.medRxiv : the preprint server for health sciences · 2025Article
- Post-stroke Stiff-Knee gait: are there different types or different severity levels?Journal of neuroengineering and rehabilitation · 2025Article
- Protocol for a multicenter prospective sequential intervention study: the effect of adaptive closed-loop postural training on gait disorders in hemiparetic stroke patients.Frontiers in neurologyArticle
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Authors and funding
7 authors.
Funding
Abstract
Stiff knee gait (SKG) occurrence after a stroke is associated with various abnormal muscle activities; however, the interactions among these muscles are unclear. This study aimed to elucidate the muscle synergy characteristics during walking in patients with SKG after a stroke. This cross-sectional study included 20 patients with poststroke SKG (SKG group), 16 patients without poststroke SKG (non-SKG group), and 15 healthy adults (control group). Participants walked a 10-m distance at a comfortable speed, and electromyographic data were recorded from six lower-limb muscles. Non-negative matrix factorization was employed to derive time-varying activity (C), muscle weights (W), and the percentage of total variance accounted for (tVAF) for muscle synergies. The SKG group showed a higher tVAF than the control group. The initial stance module (including knee extensors) showed increased activity during the swing phase. The initial swing module (including hip flexors and ankle dorsiflexors) exhibited a higher activity during the single-support phase but a lower activity during the swing phase. The synergy structure in patients with SKG after stroke was simplified, with specific abnormalities in synergy activities. SKG may arise from several synergy alterations involving multiple muscles, indicating that approaches focused on controlling individual muscle activities are unsuitable.
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