Evidence map›Paper›PMID 39217143›Full record

ArticleNature communications2024

Feedforward inhibition of stress by brainstem neuropeptide Y neurons.

Yan Zhang, Jiayi Shen, Famin Xie, Zhiwei Liu, Fangfang Yin, Mingxiu Cheng, Liang Wang, Meiting Cai, Herbert Herzog, Ping Wu and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yan Zhang *State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-7498-3105
Jiayi Shen *Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Famin XieState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0003-2055-8346
Zhiwei LiuCenter for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Fangfang YinInstitute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China.
Mingxiu ChengNational Institute of Biological Sciences, Beijing, China.
Liang WangCenter for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.ORCID 0000-0002-6856-3331
Meiting CaiHefei National Research center for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.
Herbert HerzogSt Vincent's Centre for Applied Medical Research, Faculty of Medicine, UNSW, Sydney, NSW, Australia.
Ping WuInstitute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China.
Zhi ZhangState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. z_zhang@fudan.edu.cn.ORCID 0000-0002-3222-2877
Cheng ZhanHefei National Research center for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China. zhancheng@ustc.edu.cn.ORCID 0000-0001-9397-0871
Tiemin LiuState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. tiemin_liu@fudan.edu.cn.ORCID 0000-0003-2077-7653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance to stress is a key determinant for mammalian functioning. While many studies have revealed neural circuits and substrates responsible for initiating and mediating stress responses, little is known about how the brain resists to stress and prevents overreactions. Here, we identified a previously uncharacterized neuropeptide Y (NPY) neuronal population in the dorsal raphe nucleus and ventrolateral periaqueductal gray region (DRN/vlPAG) with anxiolytic effects in male mice. NPY

Indexed as

NeuronsNeuropeptide YStress, PsychologicalAnimalsAnxietyBrain StemDorsal Raphe NucleusHypothalamic Area, LateralMaleMiceMice, Inbred C57BLPeriaqueductal GrayStress, PhysiologicalNeuropeptide Y

Identifiers

PMID39217143
PMCPMC11365948

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.