Evidence map›Paper›PMID 39217113›Full record

ArticleAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2024

Patient, Practice, and Organizational Factors Associated With Early Mobility Performance in Critically Ill Adults.

Anna E Krupp, Alai Tan, Eduard E Vasilevskis, Lorraine C Mion, Brenda T Pun, Audrey Brockman, Breanna Hetland, E Wesley Ely, Michele C Balas

Abstract read
In one paragraph

Article in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Anna E KruppAnna E. Krupp is an assistant professor, College of Nursing, University of Iowa, Iowa City.
Alai TanAlai Tan is a research professor, Center for Research and Health Analytics, The Ohio State University College of Nursing, Columbus.
Eduard E VasilevskisEduard E. Vasilevskis is a professor and chief of the Division of Hospital Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison.
Lorraine C MionLorraine C. Mion is a research professor, Center for Healthy Aging, Self-Management and Complex Care, The Ohio State University College of Nursing.
Brenda T PunBrenda T. Pun is director of data quality, Critical Illness, Brain Dysfunction, and Survivorship Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Audrey BrockmanAudrey Brockman is a graduate research assistant, The Ohio State University College of Nursing.
Breanna HetlandBreanna Hetland is an assistant professor, College of Nursing, University of Nebraska Medical Center, Omaha, and a critical care nurse scientist, Nebraska Medicine, Omaha.
E Wesley ElyE. Wesley Ely is a professor, Department of Medicine and the Critical Illness, Brain Dysfunction, and Survivorship Center, Vanderbilt University Medical Center, and associate director of medicine and research, Geriatric Research Education and Clinical Center, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee.
Michele C BalasMichele C. Balas is professor and associate dean of research, College of Nursing, University of Nebraska Medical Center.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts in the ICU (DISCOVER-ICU) studyR01HL146781 · NHLBI · OHIO STATE UNIVERSITY · PI BALAS, MICHELE CHRISTINA, MION, LORRAINE C · 2019 to 2021
$1.3M
NCATS NIH HHS UL1 TR000445NHLBI NIH HHS R01 HL146781
6 · The paper itself

Abstract

backgroundAdoption of early mobility interventions into intensive care unit (ICU) practice has been slow and varied.

objectivesTo examine factors associated with early mobility performance in critically ill adults and evaluate factors' effects on predicting next-day early mobility performance.

methodsA secondary analysis of 66 ICUs' data from patients admitted for at least 24 hours. Mixed-effects logistic regression modeling was done, with area under the receiver operating characteristic curve (AUC) calculated.

resultsIn 12 489 patients, factors independently associated with higher odds of next-day mobility included significant pain (adjusted odds ratio [AOR], 1.16; 95% CI, 1.09-1.23), documented sedation target (AOR, 1.09; 95% CI, 1.01-1.18), performance of spontaneous awakening trials (AOR, 1.77; 95% CI, 1.59-1.96), spontaneous breathing trials (AOR, 2.35; 95% CI, 2.14-2.58), mobility safety screening (AOR, 2.26; 95% CI, 2.04-2.49), and prior-day physical/occupational therapy (AOR, 1.44; 95% CI, 1.30-1.59). Factors independently associated with lower odds of next-day mobility included deep sedation (AOR, 0.44; 95% CI, 0.39-0.49), delirium (AOR, 0.63; 95% CI, 0.59-0.69), benzodiazepine administration (AOR, 0.85; 95% CI, 0.79-0.92), physical restraints (AOR, 0.74; 95% CI, 0.68-0.80), and mechanical ventilation (AOR, 0.73; 95% CI, 0.68-0.78). Black and Hispanic patients had lower odds of next-day mobility than other patients. Models incorporating patient, practice, and between-unit variations displayed high discriminant accuracy (AUC, 0.853) in predicting next-day early mobility performance.

conclusionsCollectively, several modifiable and nonmodifiable factors provide excellent prediction of next-day early mobility performance.

Indexed as

Critical IllnessEarly AmbulationIntensive Care UnitsAdultAgedCritical CareFemaleHumansLogistic ModelsMaleMiddle Aged

Identifiers

PMID39217113
PMCPMC11675296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.