Evidence map›Paper›PMID 39217084›Full record

ArticleJournal of voice : official journal of the Voice Foundation2024

Supraglottic Laryngeal Maneuvers in Adductor Laryngeal Dystonia During Connected Speech.

Maryam Naghibolhosseini, Trent M Henry, Mohsen Zayernouri, Stephanie R C Zacharias, Dimitar D Deliyski

Abstract read
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In one paragraph

Article in Journal of voice : official journal of the Voice Foundation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Creak Derived from CAPE-V Sentences in Patients with AdLd and pMTD.Journal of voice : official journal of the Voice Foundation · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maryam NaghibolhosseiniDepartment of Communicative Sciences and Disorders, Michigan State University, East Lansing, Michigan. Electronic address: naghib@msu.edu.
Trent M HenryDepartment of Communicative Sciences and Disorders, Michigan State University, East Lansing, Michigan.
Mohsen ZayernouriDepartment of Mechanical Engineering, and Statistics and Probability, Michigan State University, East Lansing, Michigan.
Stephanie R C ZachariasHead and Neck Regenerative Medicine Program, Mayo Clinic, Scottsdale, Arizona; Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Phoenix, Arizona.
Dimitar D DeliyskiDepartment of Communicative Sciences and Disorders, Michigan State University, East Lansing, Michigan.

Funding

Towards Precision Assessment of Dysphonic Speech: From Vocal Fold Physiology to PerceptionR01DC019402 · NIDCD · MICHIGAN STATE UNIVERSITY · PI DIMITAR D DELIYSKI · 2022 to 2026
$3.1M
DEIA Mentorship Supplement to Early Career Research (ECR) R21 AwardR21DC020003 · NIDCD · MICHIGAN STATE UNIVERSITY · PI NAGHIBOLHOSSEINI, MARYAM · 2022 to 2024
$899k
Studying the Laryngeal Mechanisms Underlying Dysphonia in Connected SpeechK01DC017751 · NIDCD · MICHIGAN STATE UNIVERSITY · PI NAGHIBOLHOSSEINI, MARYAM · 2019 to 2023
$689k
NIDCD NIH HHS K01 DC017751NIDCD NIH HHS R01 DC019402NIDCD NIH HHS R21 DC020003
6 · The paper itself

Abstract

objectiveAdductor laryngeal dystonia (AdLD) disrupts fine motor movements of vocal folds during speech, resulting in a strained, broken, and strangled voice. Laryngeal high-speed videoendoscopy (HSV) in connected speech enables the direct visualization of detailed laryngeal dynamics, hence, it can be effectively used to study AdLD. The current study utilizes HSV to investigate supraglottic laryngeal tissue maneuvers obstructing the view of the vocal folds, in AdLD and normophonic speakers during connected speech. Characterizing the laryngeal maneuvers in these groups can facilitate a deeper understanding of the normophonic voice physiology and AdLD voice pathophysiology.

methodsHSV data were obtained from six normophonic speakers and six patients with AdLD during production of connected speech. Three experienced raters visually analyzed the data to determine laryngeal tissues leading to obstructions of vocal folds in HSV images. The raters recorded the duration of each obstruction and indicated the specific tissue(s) leading to the obstruction. After the completion of their individual visual analysis, the raters came to consensus about their observations and measurements.

resultsStatistical analysis indicated that AdLD patients exhibited higher occurrences of vocal fold obstructions and longer durations of obstructions compared with the normophonic group. Similar obstruction types were found in both groups, with the epiglottis being the primary site of obstruction for both. Participants with AdLD displayed significantly elevated occurrences of sphincteric compression resulting in vocal fold obstruction.

conclusionHSV can be used to study the movements of laryngeal tissues in detail during connected speech. The analysis of supraglottic laryngeal tissue dynamics in speech can help us characterize the AdLD pathophysiology. The study's findings regarding the tissues implicated in obstructions may potentially inform the development of patient-specific therapeutic strategies targeting individual control over specific laryngeal muscles during phonation and speech production.

Indexed as

Connected speechHigh-speed videoendoscopyLaryngeal dystoniaLaryngeal maneuversVocal fold obstruction

Identifiers

PMID39217084
PMCPMC11868461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.