Evidence map›Paper›PMID 39215970›Full record

ArticleHealth policy and planning2024

Qualitative system dynamics modelling to support the design and implementation of tuberculosis infection prevention and control measures in South African primary healthcare facilities.

Karin Diaconu, Aaron Karat, Fiammetta Bozzani, Nicky McCreesh, Jennifer Falconer, Anna Voce, Anna Vassall, Alison D Grant, Karina Kielmann

Abstract read
In one paragraph

Article in Health policy and planning, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karin DiaconuInstitute for Global Health and Development, Queen Margaret University, Queen Margaret University Drive, Musselburgh EH21 6UU, United Kingdom.ORCID 0000-0002-5810-9725
Aaron KaratInstitute for Global Health and Development, Queen Margaret University, Queen Margaret University Drive, Musselburgh EH21 6UU, United Kingdom.ORCID 0000-0001-9643-664X
Fiammetta BozzaniTB Centre, London School of Hygiene & Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, United Kingdom.ORCID 0000-0002-9518-6885
Nicky McCreeshTB Centre, London School of Hygiene & Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, United Kingdom.ORCID 0000-0003-1409-8531
Jennifer FalconerInstitute for Global Health and Development, Queen Margaret University, Queen Margaret University Drive, Musselburgh EH21 6UU, United Kingdom.
Anna VoceSchool of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, 238 Mazisi Kunene Rd, Glenwood, Durban 4041, South Africa.ORCID 0000-0001-9082-4449
Anna VassallTB Centre, London School of Hygiene & Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, United Kingdom.ORCID 0000-0002-2911-1375
Alison D GrantTB Centre, London School of Hygiene & Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, United Kingdom.ORCID 0000-0002-2437-5195
Karina KielmannInstitute for Global Health and Development, Queen Margaret University, Queen Margaret University Drive, Musselburgh EH21 6UU, United Kingdom.ORCID 0000-0001-5519-1658

Funding

Gcrf CCF17-7779 ES/P008011/1
6 · The paper itself

Abstract

Tuberculosis infection prevention and control (TB IPC) measures are a cornerstone of policy, but measures are diverse and variably implemented. Limited attention has been paid to the health system environment, which influences successful implementation of these measures. We used qualitative system dynamics and group-model-building methods to (1) develop a qualitative causal map of the interlinked drivers of Mycobacterium tuberculosis (Mtb) transmission in South African primary healthcare facilities, which in turn helped us to (2) identify plausible IPC interventions to reduce risk of transmission. Two 1-day participatory workshops were held in 2019 with policymakers and decision makers at national and provincial levels and patient advocates and health professionals at clinic and district levels. Causal loop diagrams were generated by participants and combined by investigators. The research team reviewed diagrams to identify the drivers of nosocomial transmission of Mtb in primary healthcare facilities. Interventions proposed by participants were mapped onto diagrams to identify anticipated mechanisms of action and effect. Three systemic drivers were identified: (1) Mtb nosocomial transmission is driven by bottlenecks in patient flow at given times; (2) IPC implementation and clinic processes are anchored within a staff 'culture of nominal compliance'; and (3) limited systems learning at the policy level inhibits effective clinic management and IPC implementation. Interventions prioritized by workshop participants included infrastructural, organizational and behavioural strategies that target three areas: (1) improve air quality, (2) improve use of personal protective equipment and (3) reduce the number of individuals in the clinic. In addition to core mechanisms, participants elaborated specific additional enablers who would help sustain implementation. Qualitative system dynamics modelling methods allowed us to capture stakeholder views and potential solutions to address the problem of sub-optimal TB IPC implementation. The participatory elements of system dynamics modelling facilitated problem-solving and inclusion of multiple factors frequently neglected when considering implementation.

Indexed as

Primary Health CareTuberculosisCross InfectionHealth FacilitiesHumansInfection ControlMycobacterium tuberculosisQualitative ResearchSouth Africainfection prevention and controlnosocomial transmissionparticipatory group model-buildingSouth AfricaSystem dynamics modellingtuberculosis

Identifiers

PMID39215970
PMCPMC11562122

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.