Evidence map›Paper›PMID 39215928›Full record

ArticleJournal of molecular histology2024

Biotoxicity of paraquat to lung cells mediated by endoplasmic reticulum-mitochondria interaction.

Ping Xiao, Shaohua Wu, Zhiyong Wang, Guoqiang Shen, Xiaofeng Shi

Abstract read
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In one paragraph

Article in Journal of molecular histology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ping XiaoClinical Laboratory, Tianjin First Central Hospital, Tianjin, 300192, China.
Shaohua WuClinical Laboratory, Tianjin First Central Hospital, Tianjin, 300192, China.
Zhiyong WangDepartment of Emergency, Tianjin First Central Hospital, Tianjin, 300192, China.
Guoqiang ShenDepartment of Emergency, Tianjin First Central Hospital, Tianjin, 300192, China.
Xiaofeng ShiDepartment of Emergency, Tianjin First Central Hospital, Tianjin, 300192, China. sxf74@sohu.com.

Funding

the Key Health Science and Technology Research Program of Tianjin NO. CM2020
6 · The paper itself

Abstract

The high lethality caused by paraquat (PQ) poisoning has attracted much attention in public and human health due to its high toxicity and lethality. However, the understanding of the mechanism of PQ-induced apoptosis from the perspective of organelles, especially inter-organelle interactions, is still scarce. Exploring the linkage of multiple organelles during PQ poisoning and the molecular mechanisms of PQ poisoning under its mediation will help to gain insight into the mode of PQ poisoning at the organelle level. In this study, we observed that a certain dose of PQ gavage induced oxidative stress, mitochondrial dysfunction and endoplasmic reticulum stress in rat lung tissue cells. PQ toxicity led to the occurrence of Ca

Indexed as

ApoptosisCalciumEndoplasmic ReticulumEndoplasmic Reticulum StressLungMitochondriaOxidative StressParaquatAnimalsMaleRatsCalciumParaquatCa2+ axisEndoplasmic reticulum stressMitochondrial dysfunctionMolecular mechanismsParaquat

Identifiers

PMID39215928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.