Evidence map›Paper›PMID 39215823›Full record

ArticleActa diabetologica2024

Treating hyperglycaemia in a patient with maternally inherited diabetes and deafness with an inhibitor of dipeptidyl peptidase-4: a case report and two-year follow-up.

Lingjun Sun, Xianjiang Li, Honglei Li, Li Peng

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In one paragraph

Article in Acta diabetologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lingjun SunDepartment of Endocrinology, The Fourth Affiliated Hospital of Nanjing Medical University, Nanpu Road 298, Nanjing, China.
Xianjiang LiDepartment of Endocrinology, Nanjing Qixia District Hospital, Yaojia Road 28, Nanjing, China.
Honglei LiDepartment of Endocrinology, The Fourth Affiliated Hospital of Nanjing Medical University, Nanpu Road 298, Nanjing, China.
Li PengDepartment of Endocrinology, The Fourth Affiliated Hospital of Nanjing Medical University, Nanpu Road 298, Nanjing, China. penglee@njmu.edu.cn.ORCID http://orcid.org/0009-0000-5017-1690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder with diverse characteristics, which make early diagnosis difficult. We report a case of 32-year-old woman with diabetes who was admitted due to weight loss and poor glycemic control. She had a history of gestational diabetes at age 26. Pancreatic function was evaluated by oral glucose tolerance. An ophthalmologic examination detected conjunctivitis and refractive errors and hearing tests were normal. The patient had a family of diabetes. Then we tested the patient and her first-degree relatives with a confirmed genetic mutation at position 3243 in the tRNA. After two years of treatment with linagliptin, both glycated hemoglobin and pancreatic function have shown improvement to some extent. Although MIDD is a rare form of diabetes, due to distinctive management and associated comorbidities it is important to diagnose.

Indexed as

DeafnessDipeptidyl-Peptidase IV InhibitorsHyperglycemiaAdultDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansMitochondrial DiseasesDipeptidyl-Peptidase IV InhibitorsGenetic testingLinagliptinMaternally inherited diabetes and deafnessMitochondrial disorder

Identifiers

PMID39215823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.