Evidence map›Paper›PMID 39215799›Full record

ArticleExtremophiles : life under extreme conditions2024

Molecular basis of hyper-thermostability in the thermophilic archaeal aldolase MfnB.

Rosie M A Maddock, Carl O Marsh, Samuel T Johns, Lynden D Rooms, Phillip W Duke, Marc W van der Kamp, James E M Stach, Paul R Race

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Extremophiles : life under extreme conditions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosie M A Maddock *School of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, BS8 1TD, UK.
Carl O Marsh *School of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, BS8 1TD, UK.
Samuel T JohnsSchool of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, BS8 1TD, UK.
Lynden D RoomsSchool of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, BS8 1TD, UK.
Phillip W DukeDefence Science and Technology Laboratory, Porton Down, Salisbury, SP4 0JQ, UK.
Marc W van der KampSchool of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, BS8 1TD, UK.
James E M StachSchool of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK.
Paul R RaceSchool of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK. paul.race1@newcastle.ac.uk.ORCID http://orcid.org/0000-0003-0184-5630

Funding

Biotechnology and Biological Sciences Research Council BB/L01386X/1Biotechnology and Biological Sciences Research Council BB/M025624/1Biotechnology and Biological Sciences Research Council BB/T001968/1Defence Science and Technology Laboratory DSTLX1000098188Defence Science and Technology Laboratory DSTLX1000133108Engineering and Physical Sciences Research Council EP/L016494/1
6 · The paper itself

Abstract

Methanogenic archaea are chemolithotrophic prokaryotes that can reduce carbon dioxide with hydrogen gas to form methane. These microorganisms make a significant contribution to the global carbon cycle, with methanogenic archaea from anoxic environments estimated to contribute > 500 million tons of global methane annually. Archaeal methanogenesis is dependent on the methanofurans; aminomethylfuran containing coenzymes that act as the primary C

Indexed as

Archaeal ProteinsEnzyme StabilityMethanocaldococcusAldehyde-LyasesHot TemperatureMethanococcusMolecular Dynamics SimulationThermotoleranceAldehyde-LyasesArchaeal ProteinsAldolaseMethanofuranMethanogenesisProtein foldingThermostability

Identifiers

PMID39215799
PMCPMC11365854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.