Evidence map›Paper›PMID 39215397›Full record

ArticleAnnals of clinical and translational neurology2024

In-hospital recurrent stroke in ipsilateral carotid web patients undergoing thrombectomy.

Farhan Khan, Narendra Kala, Kelvin Chang, Liqi Shu, Eric D Goldstein, Radmehr Torabi, Krisztina Moldovan, Mahesh Jayaraman, Nahid Mohammadzadeh, Karen Furie and 1 more

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In one paragraph

Article in Annals of clinical and translational neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. When thrombus points to the culprit and meets middle cerebral artery anomalies.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Farhan KhanDepartment of Neurology, Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-5958-6881
Narendra KalaDepartment of Neurology, Brown University, Providence, Rhode Island, USA.
Kelvin ChangDepartment of Neurology, Brown University, Providence, Rhode Island, USA.
Liqi ShuDepartment of Neurology, Brown University, Providence, Rhode Island, USA.
Eric D GoldsteinDepartment of Neurology, Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-2297-495X
Radmehr TorabiDepartment of Neurosurgery, Brown University, Providence, Rhode Island, USA.
Krisztina MoldovanDepartment of Neurosurgery, Brown University, Providence, Rhode Island, USA.
Mahesh JayaramanDepartment of Radiology, Brown University, Providence, Rhode Island, USA.
Nahid MohammadzadehDepartment of Neurology, Brown University, Providence, Rhode Island, USA.
Karen FurieDepartment of Neurology, Brown University, Providence, Rhode Island, USA.
Shadi YaghiDepartment of Neurology, Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-0031-1004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCarotid artery web is a possible cause of ischemic stroke, especially in young patients who lack conventional risk factors. The immediate and long-term outcomes are not well studied. We aimed to determine the association between an ipsilateral carotid web and in-hospital stroke recurrence.

methodsWe analyzed data from adult patients admitted with an acute anterior circulation large vessel occlusion at a Comprehensive Stroke Center between July 2015 and March 2023. The primary outcome was in-hospital stroke recurrence and secondary outcome was in-hospital recurrent LVO. Multivariable logistic regression was performed to examine the association between ipsilateral carotid web and recurrent ischemic stroke and recurrent LVO.

resultsOf the 1463 patients with anterior circulation large vessel occlusion, 27 (1.8%) had an ipsilateral carotid artery web. Patients with carotid web were younger (median age (IQR), 60 years (53-67 years) versus 74 years (62-84 years), P < 0.01) and less likely to be Caucasian (60% vs. 80%, p = 0.014). Of the 27 patients with carotid web, 18 (70%) had no identifiable competing stroke mechanism. When compared to patients without ipsilateral carotid web, those with an ipsilateral carotid web had a higher risk of recurrent ischemic stroke (adjusted RR: 4.38, 95% CI: 1.38-13.85) and recurrent ipsilateral large vessel occlusion (adjusted RR: 4.49, 95% CI: 1.41-14.21).

interpretationCarotid webs are an under recognized cause of acute large vessel occlusion and are associated with higher risk of early recurrence. Studies are needed to validate our findings and test early revascularization strategies in patients with symptomatic carotid artery webs.

Indexed as

Ischemic StrokeRecurrenceThrombectomyAgedAged, 80 and overCarotid Artery DiseasesFemaleHumansMaleMiddle AgedRetrospective StudiesStroke

Identifiers

PMID39215397
PMCPMC11537123

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