ArticleBMC public health2024
Sex differences in association of healthy eating pattern with all-cause mortality and cardiovascular mortality.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- A Systems Perspective on Lifestyle Behaviors, Excess Weight, and Healthy Longevity in the European Union.Nutrients · 2026Observational
- Cardiovascular disease in women: traditional and sex-specific risk factors.European heart journal · 2026Review
- Adherence to the Dietary Approaches to Stop Hypertension score and cardiovascular disease risk in Korean adults: a prospective cohort study using marginal structural models.The American journal of clinical nutrition · 2026Article
- Socio-Demographic Variation in Adherence to the Eatwell Guide Within the UK Biobank Prospective Cohort Study.Nutrition bulletin · 2026Article
- Planetary health diet: dissecting the link between diet, mortality risk and heart age from a 16-year follow-up of the Guangzhou Biobank Cohort Study.European journal of nutrition · 2026Article
- Article
- Associations of dietary indices with risk of all-cause and cardiovascular mortality in hypertensive adults.Annals of medicine · 2025Article
- Association of the triglyceride-glucose index combined with a body shape index with all-cause and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic syndrome stage 0-3: findings from two prospective cohorts.Cardiovascular diabetology · 2025Observational
- Dietary patterns and accelerated multimorbidity in older adults.Nature aging · 2025Article
- Nutrient-Wide Association Study for Dementia Risks: A Prospective Cohort Study in Middle-Aged and Older Adults.Nutrients · 2025Article
- Dietary intake of live microbes mitigates the mortality risk associated with sedentary behavior in US hypertensive individuals.Scientific reports · 2025Article
- Associations of polyunsaturated fatty acids and genetic predisposition with cardiovascular risk among hypertensive adults.Frontiers in nutrition · 2025Article
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Authors and funding
8 authors.
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Abstract
backgroundAlthough the Healthy Eating Index (HEI) is widely recommended to reduce the risk of cardiovascular disease and all-cause death, there are significant differences in physiological and nutritional factors between the sexes. The potential impact of sex on adult dietary health is still poorly understood. The study was designed to assess whether the health benefits of diet differed by sex.
methodsIn a prospective study of 39,567 U.S. adults (51.2% female, age 46.8 ± 17.6 years), we examined sex-specific, multivariable-adjusted associations of HEI with all-cause mortality and cardiovascular disease mortality. Restricted cubic splines (RCS), subgroup analysis, propensity score matching (PSM), random forest feature importance, and sensitivity analysis were also used.
resultsDuring 328,403 person-years of follow-up, a total of 4754 all-cause deaths were recorded, including 1481 cardiovascular deaths. Compared to the lowest quartile of HEI, the all-cause mortality rate of females and males in the highest quartile array decreased by 34% (HR 0.66 [95% CI 0.55-0.8]) and 15% (HR 0.85 [95% CI 0.73-0.99]), respectively. The restricted cubic spline showed a linear inverse association between baseline HEI and all-cause mortality and CVD mortality, with similar sex-specific results. Similarly, component scores were sex-specific for mortality risk, with females benefiting more from diet. The benefits of dairy products, vegetables, and sodium scores on the risk of all-cause death were higher in males and females. However, the benefits of vegetable, sodium, and fatty acid scores on the risk of cardiovascular death were different.
conclusionsIn the adult population of the U.S., there are more opportunities for females to reduce the risk of all-cause mortality and cardiovascular mortality from the same dose of healthy dietary intake than males. These findings could reduce the risk of death by motivating the population, especially females, to consume healthy dietary components, especially vegetables and dairy products.
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