Evidence map›Paper›PMID 39214931›Full record

ArticleAnnals of hematology2024

The life threat in hematopoietic allogeneic stem cell transplantation - an interview and focus group study on health care professionals' perspectives.

Alinda Reimer, Merle Ley, Carolin Schepers, Anne Pralong, Berenike Schoerger, Raymond Voltz, Michael Hallek, Marco Herling, Udo Holtick, Steffen T Simon

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alinda ReimerFaculty of Medicine, Department of Palliative Medicine, University of Cologne, University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany. alinda.reimer@uk-koeln.de.ORCID https://orcid.org/0000-0003-1618-8784
Merle LeyFaculty of Medicine, Department of Palliative Medicine, University of Cologne, University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany.ORCID https://orcid.org/0009-0009-8654-4618
Carolin SchepersFaculty of Medicine, Department of Palliative Medicine, University of Cologne, University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany.
Anne PralongFaculty of Medicine, Department of Palliative Medicine, University of Cologne, University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany.ORCID https://orcid.org/0000-0001-8201-2344
Berenike SchoergerFaculty of Medicine, Department of Palliative Medicine, University of Cologne, University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany.ORCID https://orcid.org/0000-0002-4209-6659
Raymond VoltzFaculty of Medicine, Department of Palliative Medicine, University of Cologne, University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany.ORCID https://orcid.org/0000-0002-4761-3395
Michael HallekFaculty of Medicine, Centre for Integrated Oncology, University of Cologne, University Hospital Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-7425-4455
Marco HerlingDepartment of Hematology, Cellular Therapy, Hemostaseology, Infectious Diseases, University of Leipzig, Germany and Comprehensive Cancer Center Central Germany (CCCG) Leipzig-Jena, Leipzig, Germany.
Udo HoltickFaculty of Medicine, Centre for Integrated Oncology, University of Cologne, University Hospital Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-5543-0257
Steffen T SimonFaculty of Medicine, Department of Palliative Medicine, University of Cologne, University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany.ORCID https://orcid.org/0000-0002-6884-1813

Funding

José Carreras Leukämie-Stiftung DJCLS 21 R/2021
6 · The paper itself

Abstract

Understanding healthcare professionals' (HCPs) experiences with patients undergoing hematopoietic allogeneic stem cell transplantation (allo-HSCT) is crucial, given its dual nature of offering a hope for cure which on the other hand is accompanied by a high risk for morbidity and mortality. Yet, how HCPs experience their patients' existential threats remains unexplored. Qualitative thematic content analysis was employed to comprehend these experiences. This involved conducting three focus groups and 11 individual in-depth interviews with nurses and hematologists. We found that HCPs struggled to balance curative goals and the therapy's risks, while attempting to maintain their patients' hopes. The unpredictability of patient trajectories and their suffering burdened HCPs. Despite occasional disagreements within the team, (inter-)professional exchanges remained a crucial ressource, especially in addressing the patients' potential life threat. Team meetings and palliative care specialist supervisions were emphasized as vital for managing these challenges. HCPs sought support in communicating with patients about death-related issues and managing the transition from a curative to a palliative goal of care. Our research underscores the need for targeted support for HCPs and lays a groundwork for addressing their challenges. Trial registration number DRKS00027290 (German Clinical Trials Register). Date of trial registration January 10th, 2022.

Indexed as

Focus GroupsHematopoietic Stem Cell TransplantationAdultAttitude of Health PersonnelFemaleHealth PersonnelHumansInterviews as TopicMaleMiddle AgedPalliative CareQualitative ResearchTransplantation, HomologousAllogeneic transplantationHealth care professionalsHematopoietic stem cell transplantationMoral distressSupportive care, stem cell transplantation

Identifiers

PMID39214931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.