Evidence map›Paper›PMID 39214689›Full record

ArticleJournal of neurointerventional surgery2025

System-level trends in ischemic stroke admissions after adding endovascular stroke capabilities in community hospitals.

Prateek Kumar, Sergio Salazar-Marioni, Saagar Dhanjani, Ananya Iyyangar, Rania Abdelkhaleq, Muhammad Bilal Tariq, Arash Niktabe, Anjan N Ballekere, Ngoc Mai Le, Hussain Azeem and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Prateek KumarDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Sergio Salazar-MarioniDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Saagar DhanjaniRice University, Houston, Texas, USA.
Ananya IyyangarDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Rania AbdelkhaleqDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Muhammad Bilal TariqDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Arash NiktabeDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Anjan N BallekereDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Ngoc Mai LeDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Hussain AzeemDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Louise McCulloughDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.
Sunil A ShethDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA Sunil.A.Sheth@uth.tmc.edu.ORCID http://orcid.org/0000-0003-0602-8509
Eunyoung LeeDepartment of Neurology, McGovern Medical School at UTHealth, Houston, Texas, USA.ORCID http://orcid.org/0000-0002-9440-9119

Funding

Deep Learning Enabled Endovascular Stroke Therapy Screening in Community HospitalsR01NS121154 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GIANCARDO, LUCA, SHETH, SUNIL · 2021 to 2025
$2.2M
NINDS NIH HHS R01 NS121154
6 · The paper itself

Abstract

backgroundThere is substantial interest in adding endovascular stroke therapy (EST) capabilities in community hospitals. Here, we assess the effect of transitioning to an EST-performing hospital (EPH) on acute ischemic stroke (AIS) admissions in a large hospital system including academic and community hospitals.

methodsFrom our prospectively collected multi-institutional registry, we collected data on AIS admissions at 10 hospitals in the greater Houston area from January 2014 to December 2022: one longstanding EPH (group A), three community hospitals that transitioned to EPHs in November 2017 (group B), and six community non-EPHs that remained non-EPH (group C). Primary outcomes were trends in total AIS admissions, large vessel occlusion (LVO) and non-LVO AIS, and tissue plasminogen activator (tPA) and EST use.

resultsAmong 20 317 AIS admissions, median age was 67 (IQR 57-77) years, 52.4% were male, and median National Institutes of Health Stroke Scale (NIHSS) was 4 (IQR 1-10). During the first 12 months after EPH transition, AIS admissions increased by 1.9% per month for group B, with non-LVO stroke increasing by 4.2% per month (P<0.001). A significant change occurred for group A at the transition point for all outcomes with decreasing rates in admissions for AIS, non-LVO AIS and LVO AIS, and decreasing rates of EST and tPA treatments (P<0.001).

conclusionUpgrading to EPH status was associated with a 2% per month increase in AIS admissions during the first year post-transition for the upgrading hospitals, but decreasing volumes and treatments at the established EPH. These findings quantify the impact on AIS admissions in hospital systems with increasing EST access in community hospitals.

Indexed as

Endovascular ProceduresHospitals, CommunityIschemic StrokePatient AdmissionAgedFemaleHumansMaleMiddle AgedProspective StudiesRegistriesTissue Plasminogen ActivatorTissue Plasminogen ActivatorInterventionPoliticalStroke

Identifiers

PMID39214689
PMCPMC11868459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.