Evidence map›Paper›PMID 39214607›Full record

ArticleBiomacromolecules2024

Harnessing the Biomimetic Effect of Macromolecular Crowding in the Cell-Derived Model of Clubfoot Fibrosis.

Martina Doubková, Jarmila Knitlová, David Vondrášek, Adam Eckhardt, Tomáš Novotný, Martin Ošt'ádal, Elena Filová, Lucie Bačáková

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martina DoubkováLaboratory of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague 4, Czech Republic.ORCID 0000-0002-4955-4093
Jarmila KnitlováLaboratory of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague 4, Czech Republic.ORCID 0000-0003-4607-4497
David VondrášekLaboratory of Biomathematics, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague 4, Czech Republic.ORCID 0000-0001-6432-1012
Adam EckhardtLaboratory of Translational Metabolism, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague 4, Czech Republic.ORCID 0000-0003-4757-5226
Tomáš NovotnýDepartment of Orthopaedics, Masaryk Hospital, Socialni Pece 3316/12A, 401 13 Usti nad Labem, Czech Republic.ORCID 0000-0002-3855-0038
Martin Ošt'ádalDepartment of Orthopaedics, University Hospital Bulovka, Charles University, Budinova 67/2, 180 81 Prague 8, Czech Republic.ORCID 0000-0002-3282-9847
Elena FilováLaboratory of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague 4, Czech Republic.
Lucie BačákováLaboratory of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague 4, Czech Republic.ORCID 0000-0002-1818-9484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrotic changes in pediatric clubfoot provide an opportunity to improve corrective therapy and prevent relapses with targeted drugs. This study defines the parameters of clubfoot fibrosis and presents a unique analysis of a simple pseudo-3D

Indexed as

ClubfootCollagenFibroblastsFibrosisBiomimeticsCells, CulturedExtracellular MatrixHumansCollagen

Identifiers

PMID39214607
PMCPMC11480992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.