Evidence map›Paper›PMID 39214143›Full record

ArticleThrombosis and haemostasis2025

Handheld Point-of-Care Devices for Snakebite Coagulopathy: A Scoping Review.

Michael Abouyannis, Amy E Marriott, Emma Stars, Dianne P Kitchen, Steve Kitchen, Tim A L Woods, Benno Kreuels, John H Amuasi, Wuelton M Monteiro, Ymkje Stienstra and 5 more

Abstract readScoping Review
In one paragraph

Article in Thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michael AbouyannisCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.ORCID 0000-0003-4856-4334
Amy E MarriottCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Emma StarsCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Dianne P KitchenUK National External Quality Assessment Scheme for Blood Coagulation (UK NEQAS BC), Sheffield, United Kingdom.
Steve KitchenUK National External Quality Assessment Scheme for Blood Coagulation (UK NEQAS BC), Sheffield, United Kingdom.
Tim A L WoodsUK National External Quality Assessment Scheme for Blood Coagulation (UK NEQAS BC), Sheffield, United Kingdom.
Benno KreuelsDepartment of Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
John H AmuasiDepartment of Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Wuelton M MonteiroCollege of Health Sciences, University of the State of Amazonas, Manaus, Brazil.
Ymkje StienstraCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Subramanian SenthilkumaranDepartment of Emergency and Critical Care, Manian Medical Centre, Erode, Tamil Nadu, India.
Geoff K IsbisterClinical Toxicology Research Group, University of Newcastle, Newcastle, NSW, Australia.
David G LallooCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Stuart AinsworthCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Nicholas R CasewellCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venom-induced consumption coagulopathy (VICC) is a common complication of snakebite that is associated with hypofibrinogenemia, bleeding, disability, and death. In remote tropical settings, where most snakebites occur, the 20-minute whole blood clotting test is used to diagnose VICC. Point-of-care (POC) coagulation devices could provide an accessible means of detecting VICC that is better standardized, quantifiable, and more accurate. In this scoping review, the mechanistic reasons that previously studied POC devices have failed in VICC are considered, and evidence-based recommendations are made to prioritize certain devices for clinical validation studies. Four small studies have evaluated a POC international normalized ratio (INR) device in patients with Australian Elapid,

Indexed as

Blood CoagulationDisseminated Intravascular CoagulationPoint-of-Care SystemsSnake BitesAnimalsBlood Coagulation TestsEquipment DesignHumansInternational Normalized RatioPoint-of-Care TestingPredictive Value of TestsReproducibility of Results

Identifiers

PMID39214143
PMCPMC12040437

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.