Evidence map›Paper›PMID 39213514›Full record

ArticleOrganic letters2024

Cu-Catalyzed Asymmetric Synthesis of γ-Amino Alcohols Featuring Tertiary Carbon Stereocenters.

Alejandro Delgado, Paolo Orlando, Matteo Lanzi, Jordi Benet-Buchholz, Daniele Passarella, Arjan W Kleij

Abstract read
In one paragraph

Article in Organic letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alejandro DelgadoInstitute of Chemical Research of Catalonia (ICIQ-Cerca), the Barcelona Institute of Science and Technology (BIST), 43007 - Tarragona, Spain.ORCID 0000-0002-9812-9405
Paolo OrlandoInstitute of Chemical Research of Catalonia (ICIQ-Cerca), the Barcelona Institute of Science and Technology (BIST), 43007 - Tarragona, Spain.
Matteo LanziInstitute of Chemical Research of Catalonia (ICIQ-Cerca), the Barcelona Institute of Science and Technology (BIST), 43007 - Tarragona, Spain.
Jordi Benet-BuchholzInstitute of Chemical Research of Catalonia (ICIQ-Cerca), the Barcelona Institute of Science and Technology (BIST), 43007 - Tarragona, Spain.ORCID 0000-0003-3984-3550
Daniele PassarellaDepartment of Chemistry, Università degli Studi di Milano, Via Camillo Golgi, 19, 20133 Milano, Italy.ORCID 0000-0001-6180-9581
Arjan W KleijInstitute of Chemical Research of Catalonia (ICIQ-Cerca), the Barcelona Institute of Science and Technology (BIST), 43007 - Tarragona, Spain.ORCID 0000-0002-7402-4764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alkyne-functionalized oxetanes are presented as versatile substrates that in combination with amine reagents can be transformed into structurally diverse, chiral γ-amino alcohols featuring a tetrasubstituted tertiary stereocenter under Cu catalysis. Control experiments demonstrate the privileged nature of these oxetane precursors in terms of yield and asymmetric induction levels in the developed protocol, and postsynthetic modifications offer an easy way to access more advanced synthons.

Identifiers

PMID39213514
PMCPMC11406568

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.