ArticleThe Journal of urology2025
Long-Term Outcomes of Recurrent Bulbar Urethral Stricture Treatment With the Optilume Drug-Coated Balloon: Five-Year Results From the ROBUST I Study.
Article in The Journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Comparable is not equivalent in short-term optilume evaluation.World journal of urology · 2026Article
- Perioperative outcomes and prevalence of urethral strictures during surgery for benign prostatic hyperplasia: results from the GRAND study.World journal of urology · 2026Article
- Clinical insights: regarding "Internal urethrotomy versus Optilume™ drug-coated balloon dilatation for the management of anterior urethral strictures: morbidity comparison of the techniques".World journal of urology · 2026Article
- Article
- Environmental hazards and the risk of development of idiopathic urethral strictures.Translational andrology and urology · 2026Article
- Internal urethrotomy versus Optilume™ drug-coated balloon dilatation for the management of anterior urethral strictures: morbidity comparison of the techniques.World journal of urology · 2026Article
- Innovations in the management of urethral stricture disease: emerging and regenerative strategies.The Canadian journal of urology · 2026Review
- Efficacy of the optilume® drug-coated balloon for recurrent urethral stricture after prior urethroplasty: a 12-month multicenter follow-up study.World journal of urology · 2026Article
- Single-center prospective experience with OptilumeInternational urology and nephrology · 2026Article
- Neutrophil extracellular traps in post-traumatic urethral microenvironment promote hypertrophic urethral stricture via the TLR9/NF-kB/Smad3/IL-8 axis.Apoptosis : an international journal on programmed cell death · 2026Article
- Paclitaxel Drug-Coated Balloon (OptilumeMedicina (Kaunas, Lithuania) · 2026Review
- Case - Novel approach to complex female urethral stricture using paclitaxel-coated balloon dilation.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- A first-in-human pilot study of Wharton's jelly-derived mesenchymal stem cell injection for urethral stricture: safety and preliminary efficacy.World journal of urology · 2026Article
- Practices in urethral stricture management with drug-coated balloon dilatation: an international survey.World journal of urology · 2026Article
- Drug-Coated Balloon (OptilumeAdvances in urology · 2026Article
- Paclitaxel-Coated Balloon Dilation for Adults With Recurrent Bulbar Urethral Stricture: A Health Technology Assessment.Ontario health technology assessment series · 2026Article
- Prophylactic adjuvant therapy for postoperative recurrence of urethral stricture: a narrative review.Translational andrology and urology · 2025Review
- Practice changes in urethral stricture management in the US veteran population after the 2016 AUA guidelines.World journal of urology · 2025Article
- Optilume drug-coated balloon dilation for treatment of post-prostate cancer ablative therapy urethral stricture: a case series.Translational andrology and urology · 2025Article
- Surgical management of vesicourethral anastomotic stenosis.Investigative and clinical urology · 2025Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe report the 5-year study closeout results for the ROBUST I trial evaluating the safety and efficacy of the Optilume drug-coated balloon (DCB) for men with short, recurrent bulbar urethral strictures. MATERIALS AND
methodsAdult men with recurrent bulbar urethral strictures ≤ 2 cm long and lumen < 12F were included in the study and treated with the Optilume DCB. Outcome measures included symptom questionnaires, maximum urinary flow rate, postvoid residual, and freedom from repeat intervention. Functional success was defined as improvement in International Prostate Symptom Score ≥ 50% without re-treatment.
resultsFifty-three men were enrolled and treated, and 31 subjects completed all follow-up. Functional success was achieved in 58% (25/43) patients at 5 years. Average International Prostate Symptom Score improved from a mean of 25.2 at baseline to 7.2 at 5 years (
conclusionsIn this challenging cohort of men with failed prior endoscopic treatment, the Optilume DCB shows sustained improvement in subjective and objective voiding parameters at 5 years. Optilume is a safe and effective treatment option for appropriately selected men with recurrent bulbar urethral stricture who wish to avoid urethroplasty. Results are in line with the ROBUST III randomized controlled trial that will continue follow-up through 5 years.
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