ArticleProceedings of the National Academy of Sciences of the United States of America2024
Evolution of a bistable genetic system in fluctuating and nonfluctuating environments.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Structured Promoter Variability in Epigenetically Regulated Operons Contributes to Surface Adaptation in Salmonella.Microbial biotechnology · 2026Article
- Remorphable Architectures: Reprogramming Global Bistability through Locally Bistable Metamaterials.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Induced tolerance to UV stress drives survival heterogeneity in isogenic E. coli cell populations.Scientific reports · 2026Article
- Codon bias variation in Staphylococcus aureus.PloS one · 2026Article
- MemorySeq identifies heritable epigenetic phenotypes that initiate cell culture stress tolerance in CHO cells.iScience · 2025Article
- A population model reveals a surprising role of stochastic cell division in epigenetic memory systems.iScience · 2025Article
- Structural basis for Salmonella infection by two Microviridae phages.Communications biology · 2025Article
- Biocontrol of Phage Resistance inViruses · 2025Review
- Pseudomonas syringae Lipopolysaccharide Synthesis Gene wbpL Displays Heterogeneous Expression Within In Vitro and In Planta Populations.MicrobiologyOpen · 2025Article
- Information and fitness in two-state systems: self-replicating individuals in a fluctuating environment.ArXiv · 2025Article
- Induced tolerance to UV stress drives survival heterogeneity in isogenicbioRxiv : the preprint server for biology · 2025Article
- Priestia megaterium cells are primed for surviving lethal doses of antibiotics and chemical stress.Communications biology · 2025Article
- 100+ years of phase variation: the premier bacterial bet-hedging phenomenon.Microbiology (Reading, England) · 2025Review
- Advantage of an epigenetic switch in response to alternate environments.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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Authors and funding
6 authors.
Funding
Abstract
Epigenetic mechanisms can generate bacterial lineages capable of spontaneously switching between distinct phenotypes. Currently, mathematical models and simulations propose epigenetic switches as a mechanism of adaptation to deal with fluctuating environments. However, bacterial evolution experiments for testing these predictions are lacking. Here, we exploit an epigenetic switch in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.