Evidence map›Paper›PMID 39213174›Full record

ArticleAging2024

Leukocyte telomere length and attrition in association with disease severity in cystic fibrosis patients.

Dries S Martens, Elise J Lammertyn, Pieter C Goeminne, Kristine Colpaert, Marijke Proesmans, Bart M Vanaudenaerde, Tim S Nawrot, Lieven J Dupont

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dries S MartensCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
Elise J LammertynDepartment of Chronic Diseases and Metabolism (CHROMETA), Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium.
Pieter C GoeminneHospital VITAZ Sint-Niklaas, Sint-Niklaas, Belgium.
Kristine ColpaertDepartment of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.
Marijke ProesmansDepartment of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium.
Bart M VanaudenaerdeDepartment of Chronic Diseases and Metabolism (CHROMETA), Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium.
Tim S NawrotCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
Lieven J DupontDepartment of Chronic Diseases and Metabolism (CHROMETA), Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is characterized by chronic airway inflammation and premature aging. The link with leukocyte telomere length (LTL) as a marker of biological aging is unclear. We studied disease severity and LTL in 168 CF patients of which 85 patients had a second retrospective LTL assessment. A higher FEV

Indexed as

Cystic FibrosisLeukocytesSeverity of Illness IndexTelomereTelomere ShorteningAdolescentAdultChildCystic Fibrosis Transmembrane Conductance RegulatorFemaleHumansMaleRetrospective StudiesYoung AdultCystic Fibrosis Transmembrane Conductance Regulatorbiological agingcystic fibrosislung diseasespatient cohorttelomere length

Identifiers

PMID39213174
PMCPMC11386922

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.