Evidence map›Paper›PMID 39213164›Full record

ArticleJournal of virology2024

Variable fitness effects of bacteriophage resistance mutations in

Baptiste Gaborieau, Raphaëlle Delattre, Sandrine Adiba, Olivier Clermont, Erick Denamur, Jean-Damien Ricard, Laurent Debarbieux

Abstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Phage P100 resistance in clinical and foodborneCurrent research in microbial sciences · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Multi-strain phage induced clearance of bacterial infections.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Baptiste GaborieauUniversité Paris Cité, INSERM UMR1137, IAME, Paris, France.ORCID 0000-0002-9586-3014
Raphaëlle DelattreUniversité Paris Cité, INSERM UMR1137, IAME, Paris, France.
Sandrine AdibaInstitut de Biologie de l'ENS (IBENS), École Normale Supérieure CNRS UMR8197, Paris, France.
Olivier ClermontUniversité Paris Cité, INSERM UMR1137, IAME, Paris, France.
Erick DenamurUniversité Paris Cité, INSERM UMR1137, IAME, Paris, France.ORCID 0000-0002-7860-1717
Jean-Damien RicardUniversité Paris Cité, INSERM UMR1137, IAME, Paris, France.ORCID 0000-0003-1828-2299
Laurent DebarbieuxInstitut Pasteur, Université Paris Cité, CNRS UMR6047, Bacteriophage Bacterium Host, Paris, France.ORCID 0000-0001-6875-5758

Funding

Agence Nationale de la Recherche (ANR) ANR-19AMRB-0002Agence Nationale de Sécurité du Médicament et des Produits de Santé (ANSM) HAP-2019-S003Amicale des Anciens Internes des Hôpitaux de Paris 2017Fondation pour la Recherche Médicale (FRM) DEQ20161136698Institut Pasteur Poste Accueil APHP/IP
6 · The paper itself

Abstract

Bacteria exposed to bactericidal treatment, such as antibiotics or bacteriophages (phages), often develop resistance. While phage therapy is proposed as a solution to the antibiotic resistance crisis, the bacterial resistance emerging during phage therapy remains poorly characterized. In this study, we examined a large population of phage-resistant extra-intestinal pathogenic IMPORTANCE: This study isolated more than 50 phage-resistant mutants from both

Indexed as

Escherichia coliEscherichia coli InfectionsLipopolysaccharidesMutationPhage TherapyAnimalsBacterial CapsulesBacteriophagesColiphagesFemaleGenetic FitnessMiceVirulenceLipopolysaccharidesbacterial fitnessbacteriophage resistancelung infectionmutationsphage therapy

Identifiers

PMID39213164
PMCPMC11495123

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.