Evidence map›Paper›PMID 39213064›Full record

ArticleJournal of Alzheimer's disease : JAD2024

The Add Health Parent Study: A Biosocial Resource for the Study of Multigenerational Racial/Ethnic Disparities in Alzheimer's Disease and Alzheimer's Disease-Related Dementias.

Krista M Perreira, V Joseph Hotz, Naomi N Duke, Allison E Aiello, Daniel W Belsky, Tyson Brown, Todd Jensen, Kathleen Mullan Harris

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Krista M PerreiraCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
V Joseph HotzHarris School of Public Policy, University of Chicago, Chicago, IL, USA.
Naomi N DukeSchool of Medicine, Duke University, Durham, NC, USA.
Allison E AielloRobert N. Butler Columbia Aging Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Daniel W BelskyRobert N. Butler Columbia Aging Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Tyson BrownDepartment of Sociology, Duke University, Durham, NC, USA.
Todd JensenSchool of Social Work, University of North Carolina at Chapel Hill, NC, USA.
Kathleen Mullan HarrisCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
Add Health Parent Study: Phase IR01AG042794 · NIA · DUKE UNIVERSITY · PI HARRIS, KATHLEEN MULLAN, HOTZ, VINCENT JOSEPH · 2013 to 2017
$6.5M
Locating the Parents of Add HealthR21AG042663 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 2012 to 2013
$335k
NIA NIH HHS R01 AG042794NIA NIH HHS R21 AG042663NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

Background: Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) have increased in prevalence. Objective: This article describes the Add Health Parent Study (AHPS) Phase 2, a study of social, behavioral, and biological factors influencing healthy aging and risk for AD/ADRD, in a national sample of adults aged 58-90. Methods: Sample members are parents of the National Longitudinal Study of Adolescent to Adult Health (Add Health) cohort, initially interviewed in Add Health in midlife (1994-95). AHPS Phase 1 (2015-17) collected longitudinal data on a random subsample of parents and their spouse/partners, who were mostly Non-Hispanic (NH) White. AHPS Phase 2 will collect the same longitudinal socio-behavioral, and health survey data on all remaining NH Black and Hispanic parents (Black and Hispanic Supplement, BHS). Additionally, Phase 2 will collect cognitive and DNA data from AHPS Phase 1 and BHS sample parents and their current spouse/partners. Results: Funded by the National Institute on Aging, recruitment will occur between June 2025 and May 2026, producing an expected total AHPS sample of 5506 parents and their spouse/partners. Conclusions: The AHPS will be the first longitudinal cohort study powered to address multigenerational racial/ethnic disparities in AD/ADRD risk and protective factors across race/ethnic groups and socioeconomic strata.

Indexed as

Alzheimer DiseaseParentsAdultAgedAged, 80 and overBlack or African AmericanCohort StudiesDementiaEthnicityFemaleHealth Status DisparitiesHispanic or LatinoHumansLongitudinal StudiesMaleMiddle AgedAdd healthAlzheimer’s diseaseBlack or African AmericanDNAHispanic or Latinointergenerationalparents

Identifiers

PMID39213064
PMCPMC11492112

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.