Evidence map›Paper›PMID 39213032›Full record

ArticleeLife2024

Adverse impact of female reproductive signaling on age-dependent neurodegeneration after mild head trauma in

Changtian Ye, Ryan Ho, Kenneth H Moberg, James Q Zheng

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. EFFICIENT RIBOSOMAL RNA DEPLETION FROMWellcome open research · 2025
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Changtian YeDepartment of Cell Biology, Emory University School of Medicine, Atlanta, United States.ORCID https://orcid.org/0000-0002-5381-410X
Ryan HoCollege of Art and Science, Emory University, Atlanta, United States.
Kenneth H MobergDepartment of Cell Biology, Emory University School of Medicine, Atlanta, United States.ORCID https://orcid.org/0000-0002-9820-5543
James Q ZhengDepartment of Cell Biology, Emory University School of Medicine, Atlanta, United States.ORCID https://orcid.org/0000-0002-8093-422X

Funding

Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Vasiliki Michopoulos · 2018 to 2026
$12.2M
NIA NIH HHS U54 AG062334NIH HHS U54AG062334
6 · The paper itself

Abstract

Environmental insults, including mild head trauma, significantly increase the risk of neurodegeneration. However, it remains challenging to establish a causative connection between early-life exposure to mild head trauma and late-life emergence of neurodegenerative deficits, nor do we know how sex and age compound the outcome. Using a

Indexed as

Drosophila melanogasterAge FactorsAgingAnimalsCraniocerebral TraumaDisease Models, AnimalDrosophilaDrosophila ProteinsFemaleMaleNeurodegenerative DiseasesReproductionSex CharacteristicsSex FactorsSignal TransductionDrosophila Proteinsagingdevelopmental biologyD. melanogasterfruit fliesmild brain injurymild TBIneurodegenerationneurosciencesex differencesstress

Identifiers

PMID39213032
PMCPMC11364438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.